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Marianna Sadagurski
Marianna Sadagurski
Dirección de correo verificada de wayne.edu - Página principal
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Human IL6 enhances leptin action in mice
M Sadagurski, L Norquay, J Farhang, K D’Aquino, K Copps, MF White
Diabetologia 53, 525-535, 2010
1752010
Insulin-like growth factor 1 receptor signaling regulates skin development and inhibits skin keratinocyte differentiation
M Sadagurski, S Yakar, G Weingarten, M Holzenberger, CJ Rhodes, ...
Molecular and cellular biology 26 (7), 2675-2687, 2006
1512006
IRS2 increases mitochondrial dysfunction and oxidative stress in a mouse model of Huntington disease
M Sadagurski, Z Cheng, A Rozzo, I Palazzolo, GR Kelley, X Dong, ...
The Journal of clinical investigation 121 (10), 4070-4081, 2011
1082011
Growth hormone modulates hypothalamic inflammation in long‐lived pituitary dwarf mice
M Sadagurski, T Landeryou, G Cady, JJ Kopchick, EO List, DE Berryman, ...
Aging cell 14 (6), 1045-1054, 2015
732015
Anti‐aging drugs reduce hypothalamic inflammation in a sex‐specific manner
M Sadagurski, G Cady, RA Miller
Aging Cell 16 (4), 652-660, 2017
702017
IRS2 signaling in LepR-b neurons suppresses FoxO1 to control energy balance independently of leptin action
M Sadagurski, RL Leshan, C Patterson, A Rozzo, A Kuznetsova, ...
Cell metabolism 15 (5), 703-712, 2012
672012
Canagliflozin extends life span in genetically heterogeneous male but not female mice
RA Miller, DE Harrison, DB Allison, M Bogue, L Debarba, V Diaz, ...
JCI insight 5 (21), 2020
612020
Irs2 and Irs4 synergize in non-LepRb neurons to control energy balance and glucose homeostasis
M Sadagurski, XC Dong, MG Myers Jr, MF White
Molecular metabolism 3 (1), 55-63, 2014
542014
Hypothalamic growth hormone receptor (GHR) controls hepatic glucose production in nutrient-sensing leptin receptor (LepRb) expressing neurons
G Cady, T Landeryou, M Garratt, JJ Kopchick, N Qi, D Garcia-Galiano, ...
Molecular metabolism 6 (5), 393-405, 2017
442017
Long-lived crowded-litter mice exhibit lasting effects on insulin sensitivity and energy homeostasis
M Sadagurski, T Landeryou, M Blandino-Rosano, G Cady, L Elghazi, ...
American Journal of Physiology-Endocrinology and Metabolism 306 (11), E1305 …, 2014
382014
Integrating metabolism and longevity through insulin and IGF1 signaling
M Sadagurski, MF White
Endocrinology and Metabolism Clinics 42 (1), 127-148, 2013
382013
Insulin receptor substrate 2 plays diverse cell-specific roles in the regulation of glucose transport
M Sadagurski, G Weingarten, CJ Rhodes, MF White, E Wertheimer
Journal of Biological Chemistry 280 (15), 14536-14544, 2005
382005
Insulin receptor substrate 1 (IRS‐1) plays a unique role in normal epidermal physiology
M Sadagurski, S Nofech‐Mozes, G Weingarten, MF White, T Kadowaki, ...
Journal of cellular physiology 213 (2), 519-527, 2007
342007
Transient early food restriction leads to hypothalamic changes in the long‐lived crowded litter female mice
M Sadagurski, T Landeryou, G Cady, A Bartke, E Bernal‐Mizrachi, ...
Physiological reports 3 (4), e12379, 2015
222015
Deletion of Irs2 causes reduced kidney size in mice: role for inhibition of GSK3β?
RM Carew, M Sadagurski, R Goldschmeding, F Martin, MF White, ...
BMC Developmental Biology 10, 1-8, 2010
222010
Acarbose protects from central and peripheral metabolic imbalance induced by benzene exposure
LK Debarba, A Mulka, JBM Lima, O Didyuk, P Fakhoury, L Koshko, ...
Brain, Behavior, and Immunity 89, 87-99, 2020
212020
Neuroprotective effects of Canagliflozin: Lessons from aged genetically diverse UM‐HET3 mice
HSM Jayarathne, LK Debarba, JJ Jaboro, BC Ginsburg, RA Miller, ...
Aging Cell 21 (7), e13653, 2022
172022
17-α-Estradiol has sex-specific effects on neuroinflammation that are partly reversed by gonadectomy
LK Debarba, HSM Jayarathne, RA Miller, M Garratt, M Sadagurski
The Journals of Gerontology: Series A 77 (1), 66-74, 2022
162022
Paraventricular, subparaventricular and periventricular hypothalamic IRS4-expressing neurons are required for normal energy balance
AK Sutton, IE Gonzalez, M Sadagurski, M Rajala, C Lu, MB Allison, ...
Scientific Reports 10 (1), 5546, 2020
162020
Canagliflozin retards age-related lesions in heart, kidney, liver, and adrenal gland in genetically heterogenous male mice
JM Snyder, KM Casey, A Galecki, DE Harrison, H Jayarathne, N Kumar, ...
Geroscience 45 (1), 385-397, 2023
152023
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