Extracellular signal-regulated kinase phosphorylates tumor necrosis factor α-converting enzyme at threonine 735: a potential role in regulated shedding E Díaz-Rodríguez, JC Montero, A Esparís-Ogando, L Yuste, A Pandiella Molecular biology of the cell 13 (6), 2031, 2002 | 410 | 2002 |
Inhibition of SRC family kinases and receptor tyrosine kinases by dasatinib: possible combinations in solid tumors JC Montero, S Seoane, A Ocaña, A Pandiella Clinical cancer research 17 (17), 5546-5552, 2011 | 325 | 2011 |
Erk5 participates in neuregulin signal transduction and is constitutively active in breast cancer cells overexpressing ErbB2 A Esparís-Ogando, E Díaz-Rodríguez, JC Montero, L Yuste, P Crespo, ... Molecular and cellular biology 22 (1), 270-285, 2002 | 223 | 2002 |
Differential shedding of transmembrane neuregulin isoforms by the tumor necrosis factor-α-converting enzyme JC Montero, L Yuste, E Dı́az-Rodrı́guez, A Esparı́s-Ogando, A Pandiella Molecular and Cellular Neuroscience 16 (5), 631-648, 2000 | 215 | 2000 |
Neuregulins and cancer JC Montero, R Rodríguez-Barrueco, A Ocaña, E Díaz-Rodríguez, ... Clinical cancer research 14 (11), 3237-3241, 2008 | 149 | 2008 |
Expression of Erk5 in early stage breast cancer and association with disease free survival identifies this kinase as a potential therapeutic target JC Montero, A Ocana, M Abad, MJ Ortiz-Ruiz, A Pandiella, ... PloS one 4 (5), e5565, 2009 | 144 | 2009 |
Multifunctional role of Erk5 in multiple myeloma X Carvajal-Vergara, S Tabera, JC Montero, A Esparís-Ogando, ... Blood 105 (11), 4492-4499, 2005 | 120 | 2005 |
Aplidin, a marine organism–derived compound with potent antimyeloma activity in vitro and in vivo CS Mitsiades, EM Ocio, A Pandiella, P Maiso, C Gajate, M Garayoa, ... Cancer research 68 (13), 5216-5225, 2008 | 119 | 2008 |
P-Rex1 participates in Neuregulin-ErbB signal transduction and its expression correlates with patient outcome in breast cancer JC Montero, S Seoane, A Ocaña, A Pandiella Oncogene 30 (9), 1059-1071, 2011 | 107 | 2011 |
Zalypsis: a novel marine-derived compound with potent antimyeloma activity that reveals high sensitivity of malignant plasma cells to DNA double-strand breaks EM Ocio, P Maiso, X Chen, M Garayoa, S Alvarez-Fernandez, ... Blood, The Journal of the American Society of Hematology 113 (16), 3781-3791, 2009 | 105 | 2009 |
Activation of ErbB2 by overexpression or by transmembrane neuregulin results in differential signaling and sensitivity to herceptin L Yuste, JC Montero, A Esparís-Ogando, A Pandiella Cancer research 65 (15), 6801-6810, 2005 | 102 | 2005 |
Active kinase profiling, genetic and pharmacological data define mTOR as an important common target in triple-negative breast cancer JC Montero, A Esparís-Ogando, MF Re-Louhau, S Seoane, M Abad, ... Oncogene 33 (2), 148-156, 2014 | 96 | 2014 |
In vivo murine model of acquired resistance in myeloma reveals differential mechanisms for lenalidomide and pomalidomide in combination with dexamethasone EM Ocio, D Fernández-Lázaro, L San-Segundo, L López-Corral, ... Leukemia 29 (3), 705-714, 2015 | 94 | 2015 |
The effect of the proteasome inhibitor bortezomib on acute myeloid leukemia cells and drug resistance associated with the CD34+ immature phenotype E Colado, S Álvarez-Fernández, P Maiso, J Martín, MB Vidriales, ... Ferrata Storti Foundation, 2008 | 92 | 2008 |
Activity of BET-proteolysis targeting chimeric (PROTAC) compounds in triple negative breast cancer MM Noblejas-López, C Nieto-Jimenez, M Burgos, M Gómez-Juárez, ... Journal of Experimental & Clinical Cancer Research 38, 1-9, 2019 | 86 | 2019 |
Stimulation of cleavage of membrane proteins by calmodulin inhibitors E DÍAZ-RODRÍGUEZ, A ESPARÍS-OGANDO, JC MONTERO, L YUSTE, ... Biochemical Journal 346 (2), 359-367, 2000 | 86 | 2000 |
Neuregulin expression modulates clinical response to trastuzumab in patients with metastatic breast cancer E de Alava, A Ocana, M Abad, JC Montero, A Esparís-Ogando, ... Journal of Clinical Oncology 25 (19), 2656-2663, 2007 | 84 | 2007 |
Transforming growth factor‐β1 induces collagen synthesis and accumulation via p38 mitogen‐activated protein kinase (MAPK) pathway in cultured L6E9 myoblasts A Rodrıguez-Barbero, J Obreo, L Yuste, JC Montero, A Rodrı́guez-Peña, ... FEBS letters 513 (2-3), 282-288, 2002 | 76 | 2002 |
Targeting the EGF/HER ligand-receptor system in cancer A Esparis-Ogando, J Carlos Montero, J Arribas, A Ocana, A Pandiella Current pharmaceutical design 22 (39), 5887-5898, 2016 | 74 | 2016 |
Transcriptomic profile induced in bone marrow mesenchymal stromal cells after interaction with multiple myeloma cells: implications in myeloma progression and myeloma bone disease A Garcia-Gomez, J De Las Rivas, EM Ocio, E Díaz-Rodríguez, ... Oncotarget 5 (18), 8284, 2014 | 73 | 2014 |