| Redox signaling mediated by thioredoxin and glutathione systems in the central nervous system X Ren, L Zou, X Zhang, V Branco, J Wang, C Carvalho, A Holmgren, J Lu Antioxidants & redox signaling 27 (13), 989-1010, 2017 | 288 | 2017 |
| Selenocysteine in mammalian thioredoxin reductase and application of ebselen as a therapeutic X Ren, L Zou, J Lu, A Holmgren Free Radical Biology and Medicine 127, 238-247, 2018 | 119 | 2018 |
| Synergistic antibacterial activity of silver with antibiotics correlating with the upregulation of the ROS production L Zou, J Wang, Y Gao, X Ren, ME Rottenberg, J Lu, A Holmgren Scientific reports 8 (1), 11131, 2018 | 82 | 2018 |
| Synergistic antibacterial effect of silver and ebselen against multidrug‐resistant Gram‐negative bacterial infections L Zou, J Lu, J Wang, X Ren, L Zhang, Y Gao, ME Rottenberg, A Holmgren EMBO molecular medicine 9 (8), 1165-1178, 2017 | 79 | 2017 |
| Nitric oxide protects against infection-induced neuroinflammation by preserving the stability of the blood-brain barrier GC Olivera, X Ren, SK Vodnala, J Lu, L Coppo, C Leepiyasakulchai, ... PLoS pathogens 12 (2), e1005442, 2016 | 62 | 2016 |
| Inhibition of the glutaredoxin and thioredoxin systems and ribonucleotide reductase by mutant p53-targeting compound APR-246 L Haffo, J Lu, VJN Bykov, SS Martin, X Ren, L Coppo, KG Wiman, ... Scientific reports 8 (1), 12671, 2018 | 58 | 2018 |
| The combination of ascorbate and menadione causes cancer cell death by oxidative stress and replicative stress X Ren, SM Santhosh, L Coppo, FT Ogata, J Lu, A Holmgren Free Radical Biology and Medicine 134, 350-358, 2019 | 53 | 2019 |
| Selenium-containing thioredoxin reductase inhibitor ethaselen sensitizes non-small cell lung cancer to radiotherapy L Wang, J Fu, J Wang, C Jin, X Ren, Q Tan, J Li, H Yin, K Xiong, T Wang, ... Anti-Cancer Drugs 22 (8), 732-740, 2011 | 46 | 2011 |
| Topical Therapeutic Efficacy of Ebselen Against Multidrug-Resistant Staphylococcus aureus LT-1 Targeting Thioredoxin Reductase C Dong, J Zhou, P Wang, T Li, Y Zhao, X Ren, J Lu, J Wang, A Holmgren, ... Frontiers in Microbiology 10, 3016, 2020 | 41 | 2020 |
| Preparation of tri-block copolymer micelles loading novel organoselenium anticancer drug BBSKE and study of tissue distribution of copolymer micelles by imaging in vivo method M Liu, J Fu, J Li, L Wang, Q Tan, X Ren, Z Peng, H Zeng International journal of pharmaceutics 391 (1-2), 292-304, 2010 | 37 | 2010 |
| Oxidation of structural cysteine residues in thioredoxin 1 by aromatic arsenicals enhances cancer cell cytotoxicity caused by the inhibition of thioredoxin reductase 1 X Zhang, J Lu, X Ren, Y Du, Y Zheng, PV Ioannou, A Holmgren Free Radical Biology and Medicine 89, 192-200, 2015 | 32 | 2015 |
| The production of reactive oxygen species enhanced with the reduction of menadione by active thioredoxin reductase J Li, X Zuo, P Cheng, X Ren, S Sun, J Xu, A Holmgren, J Lu Metallomics 11 (9), 1490-1497, 2019 | 30 | 2019 |
| Thioredxin reductase inhibitor ethaselen increases the drug sensitivity of the colon cancer cell line LoVo towards cisplatin via regulation of G1 phase and reversal of G2/M … J Fu, J Li, Q Tan, H Yin, K Xiong, T Wang, X Ren, H Zeng Investigational new drugs 29, 627-636, 2011 | 30 | 2011 |
| Characterization of mammalian glutaredoxin isoforms as S‐denitrosylases X Ren, R Sengupta, J Lu, JO Lundberg, A Holmgren FEBS letters 593 (14), 1799-1806, 2019 | 26 | 2019 |
| Targeting bacterial antioxidant systems for antibiotics development X Ren, L Zou, A Holmgren Current Medicinal Chemistry 27 (12), 1922-1939, 2020 | 24 | 2020 |
| Inhibition of thioredoxin reductase 1 correlates with platinum-based chemotherapeutic induced tissue injury P Cheng, H Liu, Y Li, P Pi, Y Jiang, S Zang, X Li, A Fu, X Ren, J Xu, ... Biochemical pharmacology 175, 113873, 2020 | 20 | 2020 |
| Modulating antioxidant systems as a therapeutic approach to retinal degeneration X Ren, T Léveillard Redox Biology 57, 102510, 2022 | 15 | 2022 |
| Selenium Status in Diet Affects Acetaminophen-Induced Hepatotoxicity via Interruption of Redox Environment J Li, P Cheng, S Li, P Zhao, B Han, X Ren, JL Zhong, MD Lloyd, ... Antioxidants & Redox Signaling 34 (17), 1355-1367, 2021 | 13 | 2021 |
| Novel mechanism of ethaselen in poorly differentiated colorectal RKO cell growth inhibition: Simultaneous regulation of TrxR transcription, expression and enzyme activity H Yin, J Li, K Xiong, L Wang, T Wang, Q Tan, J Fu, X Ren, H Zeng Differentiation 81 (1), 49-56, 2011 | 12 | 2011 |
| A fluorescent probe for specifically measuring the overall thioredoxin and glutaredoxin reducing activity in bacterial cells X Zuo, Y Zhao, J Zhao, Y Ouyang, W Qian, Y Hou, C Yu, X Ren, L Zou, ... Analyst 147 (5), 834-840, 2022 | 9 | 2022 |
arne holmgrenprofessor i biokemi , Karolinska InstitutetVerified email at ki.se
