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Cleo Kontoravdi
Cleo Kontoravdi
Professor of Biological Systems Engineering, Imperial College London
Dirección de correo verificada de imperial.ac.uk
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Amino acid and glucose metabolism in fed‐batch CHO cell culture affects antibody production and glycosylation
Y Fan, I Jimenez Del Val, C Müller, J Wagtberg Sen, SK Rasmussen, ...
Biotechnology and bioengineering 112 (3), 521-535, 2015
2222015
Towards the implementation of quality by design to the production of therapeutic monoclonal antibodies with desired glycosylation patterns
IJ Del Val, C Kontoravdi, JM Nagy
Biotechnology progress 26 (6), 1505-1527, 2010
1812010
Emerging technologies for low‐cost, rapid vaccine manufacture
Z Kis, R Shattock, N Shah, C Kontoravdi
Biotechnology journal 14 (1), 1800376, 2019
1412019
A dynamic mathematical model for monoclonal antibody N‐linked glycosylation and nucleotide sugar donor transport within a maturing Golgi apparatus
I Jimenez del Val, JM Nagy, C Kontoravdi
Biotechnology progress 27 (6), 1730-1743, 2011
1382011
Resources, production scales and time required for producing RNA vaccines for the global pandemic demand
Z Kis, C Kontoravdi, R Shattock, N Shah
Vaccines 9 (1), 3, 2020
1292020
How does mild hypothermia affect monoclonal antibody glycosylation?
SN Sou, C Sellick, K Lee, A Mason, S Kyriakopoulos, KM Polizzi, ...
Biotechnology and Bioengineering 112 (6), 1165-1176, 2015
1212015
‘Closing the loop’in biological systems modeling—From the in silico to the in vitro
A Kiparissides, M Koutinas, C Kontoravdi, A Mantalaris, EN Pistikopoulos
Automatica 47 (6), 1147-1155, 2011
1062011
Application of global sensitivity analysis to determine goals for design of experiments: an example study on antibody‐producing cell cultures
C Kontoravdi, SP Asprey, EN Pistikopoulos, A Mantalaris
Biotechnology progress 21 (4), 1128-1135, 2005
1012005
The role of ER stress-induced apoptosis in neurodegeneration
I C Stefani, D Wright, K M Polizzi, C Kontoravdi
Current Alzheimer Research 9 (3), 373-387, 2012
932012
Towards controlling the glycoform: a model framework linking extracellular metabolites to antibody glycosylation
PM Jedrzejewski, IJ Del Val, A Constantinou, A Dell, SM Haslam, ...
International journal of molecular sciences 15 (3), 4492-4522, 2014
922014
Rapid development and deployment of high‐volume vaccines for pandemic response
Z Kis, C Kontoravdi, AK Dey, R Shattock, N Shah
Journal of advanced manufacturing and processing 2 (3), e10060, 2020
742020
Systematic development of predictive mathematical models for animal cell cultures
C Kontoravdi, EN Pistikopoulos, A Mantalaris
Computers & Chemical Engineering 34 (8), 1192-1198, 2010
742010
A multi‐pronged investigation into the effect of glucose starvation and culture duration on fed‐batch CHO cell culture
Y Fan, I Jimenez Del Val, C Müller, AM Lund, JW Sen, SK Rasmussen, ...
Biotechnology and bioengineering 112 (10), 2172-2184, 2015
692015
Model‐based optimization of antibody galactosylation in CHO cell culture
P Kotidis, P Jedrzejewski, SN Sou, C Sellick, K Polizzi, IJ Del Val, ...
Biotechnology and bioengineering 116 (7), 1612-1626, 2019
632019
Harnessing the potential of artificial neural networks for predicting protein glycosylation
P Kotidis, C Kontoravdi
Metabolic engineering communications 10, e00131, 2020
592020
Genetically-encoded biosensors for monitoring cellular stress in bioprocessing
KM Polizzi, C Kontoravdi
Current opinion in biotechnology 31, 50-56, 2015
582015
Development of a dynamic model of monoclonal antibody production and glycosylation for product quality monitoring
C Kontoravdi, SP Asprey, EN Pistikopoulos, A Mantalaris
Computers & chemical engineering 31 (5-6), 392-400, 2007
572007
An optimized method for extraction and quantification of nucleotides and nucleotide sugars from mammalian cells
IJ del Val, S Kyriakopoulos, KM Polizzi, C Kontoravdi
Analytical biochemistry 443 (2), 172-180, 2013
562013
In situ monitoring of intracellular glucose and glutamine in CHO cell culture
A Behjousiar, C Kontoravdi, KM Polizzi
PLoS One 7 (4), e34512, 2012
552012
The era of big data: Genome-scale modelling meets machine learning
A Antonakoudis, R Barbosa, P Kotidis, C Kontoravdi
Computational and Structural Biotechnology Journal 18, 3287-3300, 2020
532020
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Artículos 1–20