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Claudio Cavasotto
Claudio Cavasotto
Translational Medicine Research Institute, CONICET-Universidad Austral
Verified email at austral.edu.ar
Title
Cited by
Cited by
Year
Homology modeling in drug discovery: current trends and applications
CN Cavasotto, SS Phatak
Drug discovery today 14 (13-14), 676-683, 2009
5632009
Protein flexibility in ligand docking and virtual screening to protein kinases
CN Cavasotto, RA Abagyan
Journal of molecular biology 337 (1), 209-225, 2004
5192004
Representing receptor flexibility in ligand docking through relevant normal modes
CN Cavasotto, JA Kovacs, RA Abagyan
Journal of the American Chemical Society 127 (26), 9632-9640, 2005
3472005
Glucocorticoid receptor phosphorylation differentially affects target gene expression
W Chen, T Dang, RD Blind, Z Wang, CN Cavasotto, AB Hittelman, ...
Molecular Endocrinology 22 (8), 1754-1766, 2008
3342008
Ligand docking and structure-based virtual screening in drug discovery
CN Cavasotto, W Orry, J Andrew
Current topics in medicinal chemistry 7 (10), 1006-1014, 2007
3242007
Discovery of novel chemotypes to a G-protein-coupled receptor through ligand-steered homology modeling and structure-based virtual screening
CN Cavasotto, AJW Orry, NJ Murgolo, MF Czarniecki, SA Kocsi, ...
Journal of medicinal chemistry 51 (3), 581-588, 2008
1942008
Exponential consensus ranking improves the outcome in docking and receptor ensemble docking
K Palacio-Rodríguez, I Lans, CN Cavasotto, P Cossio
Scientific reports 9 (1), 5142, 2019
1272019
High throughput screening for inhibitors of the HECT ubiquitin E3 ligase ITCH identifies antidepressant drugs as regulators of autophagy
M Rossi, B Rotblat, K Ansell, I Amelio, M Caraglia, G Misso, F Bernassola, ...
Cell death & disease 5 (5), e1203, 2014
1222014
Ligand and decoy sets for docking to G protein-coupled receptors
EA Gatica, CN Cavasotto
Journal of chemical information and modeling 52 (1), 1-6, 2012
1182012
Open challenges in structure-based virtual screening: Receptor modeling, target flexibility consideration and active site water molecules description
F Spyrakis, CN Cavasotto
Archives of biochemistry and biophysics 583, 105-119, 2015
1122015
High-throughput and in silico screenings in drug discovery
SS Phatak, CC Stephan, CN Cavasotto
Expert opinion on drug discovery 4 (9), 947-959, 2009
1102009
Phosphorylation of liver X receptor α selectively regulates target gene expression in macrophages
IP Torra, N Ismaili, JE Feig, CF Xu, C Cavasotto, R Pancratov, I Rogatsky, ...
Molecular and cellular biology 28 (8), 2626-2636, 2008
1102008
In silico Drug Repurposing for COVID‐19: Targeting SARS‐CoV‐2 Proteins through Docking and Consensus Ranking
CN Cavasotto, JI Di Filippo
Molecular Informatics 40 (1), 2000115, 2021
1082021
Structure‐based identification of binding sites, native ligands and potential inhibitors for G‐protein coupled receptors
CN Cavasotto, AJW Orry, RA Abagyan
Proteins: Structure, Function, and Bioinformatics 51 (3), 423-433, 2003
1032003
In silico identification of novel EGFR inhibitors with antiproliferative activity against cancer cells
CN Cavasotto, MA Ortiz, RA Abagyan, FJ Piedrafita
Bioorganic & medicinal chemistry letters 16 (7), 1969-1974, 2006
1022006
Structure-based development of target-specific compound libraries
AJW Orry, RA Abagyan, CN Cavasotto
Drug discovery today 11 (5-6), 261-266, 2006
1012006
Isoform selectivity of adenylyl cyclase inhibitors: characterization of known and novel compounds
CS Brand, HJ Hocker, AA Gorfe, CN Cavasotto, CW Dessauer
Journal of Pharmacology and Experimental Therapeutics 347 (2), 265-275, 2013
922013
2, 3‐Dihydro‐1‐Benzofuran Derivatives as a Series of Potent Selective Cannabinoid Receptor 2 Agonists: Design, Synthesis, and Binding Mode Prediction through Ligand‐Steered …
P Diaz, SS Phatak, J Xu, FR Fronczek, F Astruc‐Diaz, CM Thompson, ...
ChemMedChem 4 (10), 1615-1629, 2009
912009
Docking-based virtual screening for ligands of G protein-coupled receptors: not only crystal structures but also in silico models
S Vilar, G Ferino, SS Phatak, B Berk, CN Cavasotto, S Costanzi
Journal of Molecular Graphics and Modelling 29 (5), 614-623, 2011
882011
Accurate transferable model for water, n-octanol, and n-hexadecane solvation free energies
AJ Bordner, CN Cavasotto, RA Abagyan
The Journal of Physical Chemistry B 106 (42), 11009-11015, 2002
882002
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