Intermolecular reactions of electron-rich heterocycles with copper and rhodium carbenoids HML Davies, SJ Hedley Chemical Society Reviews 36 (7), 1109-1119, 2007 | 280 | 2007 |
Investigation into Factors Influencing Stereoselectivity in the Reactions of Heterocycles with Donor− Acceptor-Substituted Rhodium Carbenoids SJ Hedley, DL Ventura, PM Dominiak, CL Nygren, HML Davies The Journal of Organic Chemistry 71 (14), 5349-5356, 2006 | 102 | 2006 |
Development of a [3+ 3] cycloaddition strategy toward functionalized piperidines SJ Hedley, WJ Moran, DA Price, JPA Harrity The Journal of Organic Chemistry 68 (11), 4286-4292, 2003 | 91* | 2003 |
Asymmetric Intermolecular C− H Functionalization of Benzyl Silyl Ethers Mediated by Chiral Auxiliary-Based Aryldiazoacetates and Chiral Dirhodium Catalysts HML Davies, SJ Hedley, BR Bohall The Journal of Organic Chemistry 70 (26), 10737-10742, 2005 | 60 | 2005 |
Metal-free blue-light-mediated cyclopropanation of indoles by aryl (diazo) acetates X Zhang, C Du, H Zhang, XC Li, YL Wang, JL Niu, MP Song Synthesis 51 (04), 889-898, 2019 | 48 | 2019 |
Synthesis of functionalised piperidines through a [3+ 3] cycloaddition strategy SJ Hedley, WJ Moran, AHGP Prenzel, DA Price, JPA Harrity Synlett 2001 (10), 1596-1598, 2001 | 47 | 2001 |
Oxopyrido[2,3-d]pyrimidines as Covalent L858R/T790M Mutant Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors RP Wurz, LH Pettus, K Ashton, J Brown, JJ Chen, B Herberich, FT Hong, ... ACS Medicinal Chemistry Letters 6 (9), 987-992, 2015 | 30 | 2015 |
Formal synthesis of (±)-perhydrohistrionicotoxin via a stepwise [3+ 3] annelation strategy OY Provoost, SJ Hedley, AJ Hazelwood, JPA Harrity Tetrahedron letters 47 (3), 331-333, 2006 | 27 | 2006 |
Development of a practical synthesis of a pyrazolopyridinone-based p38 MAP kinase inhibitor RR Milburn, OR Thiel, M Achmatowicz, X Wang, J Zigterman, C Bernard, ... Organic Process Research & Development 15 (1), 31-43, 2011 | 23 | 2011 |
Vinyl Sulfoxonium Ylide: A New Vinyl Carbenoid Transfer Reagent for the Synthesis of Heterocycles J Vaitla, A Bayer, KH Hopmann Synlett 30 (12), 1377-1383, 2019 | 17 | 2019 |
Development of a Commercial Manufacturing Process for Sotorasib, a First-in-Class KRASG12C Inhibitor L Zhang, DJ Griffin, MG Beaver, LE Blue, CJ Borths, DB Brown, S Caille, ... Organic Process Research & Development 26 (11), 3115-3125, 2022 | 15 | 2022 |
Xantphos as a Branch-Selective Ligand for the Acyclic sec-Alkyl Negishi Cross-Coupling of Heteroaryl Halides AH Cherney, SJ Hedley, SM Mennen, JS Tedrow Organometallics 38 (1), 97-102, 2018 | 15 | 2018 |
Triazole agonists of the APJ receptor N Chen, X Chen, Y Chen, AC Cheng, RV Connors, J Deignan, ... US Patent 9,868,721, 2018 | 14 | 2018 |
Triazole agonists of the APJ receptor N Chen, X Chen, Y Chen, AC Cheng, RV Connors, J Deignan, ... US Patent 9,573,936, 2017 | 14 | 2017 |
Untitled N Chen, X Chen, Y Chen, AC Cheng, RV Connors, J Deignan, ... WO Patent 2016187308:A1, 2016 | 14* | 2016 |
Heterocyclic triazole compounds as agonists of the APJ receptor X Chen, Y Chen, AC Cheng, RV Connors, MV DeBenedetto, ... US Patent 9,988,369, 2018 | 13 | 2018 |
Intermediates for preparing triazole agonists of the APJ receptor N Chen, X Chen, AC Cheng, RV Connors, J Deignan, PJ Dransfield, X Du, ... US Patent 9,845,310, 2017 | 13 | 2017 |
Methods for preparing triazole agonists of the APJ receptor N Chen, X Chen, RV Connors, J Deignan, PJ Dransfield, X Du, Z Fu, ... US Patent 9,751,864, 2017 | 13 | 2017 |
Triazole agonists of the APJ receptor N Chen, X Chen, Y Chen, AC Cheng, RV Connors, J Deignan, ... US Patent 9,745,286, 2017 | 13 | 2017 |
Triazole agonists of the APJ receptor N Chen, X Chen, AC Cheng, RV Connors, J Deignan, PJ Dransfield, X Du, ... US Patent 9,656,997, 2017 | 13 | 2017 |