| Oxadiazoles in medicinal chemistry J Boström, A Hogner, A Llinąs, E Wellner, AT Plowright Journal of medicinal chemistry 55 (5), 1817-1830, 2012 | 637 | 2012 |
| Polymorph control: past, present and future A Llinąs, JM Goodman Drug Discovery Today 13 (5-6), 198-210, 2008 | 398 | 2008 |
| Solubility challenge: can you predict solubilities of 32 molecules using a database of 100 reliable measurements? A Llinąs, RC Glen, JM Goodman Journal of chemical information and modeling 48 (7), 1289-1303, 2008 | 216 | 2008 |
| Diclofenac solubility: independent determination of the intrinsic solubility of three crystal forms A Llinas, JC Burley, KJ Box, RC Glen, JM Goodman Journal of medicinal chemistry 50 (5), 979-983, 2007 | 155 | 2007 |
| Findings of the challenge to predict aqueous solubility. AJ Hopfinger, EX Esposito, A Llinas, RC Glen, JM Goodman Journal of chemical information and modeling 49 (1), 1-5, 2009 | 134 | 2009 |
| Predicting intrinsic aqueous solubility by a thermodynamic cycle DS Palmer, A Llinąs, I Morao, GM Day, JM Goodman, RC Glen, ... Molecular Pharmaceutics 5 (2), 266-279, 2008 | 129 | 2008 |
| Beyond size, ionization state, and lipophilicity: influence of molecular topology on absorption, distribution, metabolism, excretion, and toxicity for druglike compounds Y Yang, O Engkvist, A Llinąs, H Chen Journal of medicinal chemistry 55 (8), 3667-3677, 2012 | 124 | 2012 |
| Equilibrium solubility measurement of ionizable drugs – consensus recommendations for improving data quality KTN Alex Avdeef, Elisabet Fuguet, Antonio Llinąs, Clara Rąfols, Elisabeth ... ADMET and DMPK 4 (2), 117, 2016 | 119 | 2016 |
| Effects of trkB and trkC neurotrophin receptor agonists on thermal nociception: a behavioral and electrophysiological study XQ Shu, A Llinas, LM Mendell Pain 80 (3), 463-470, 1999 | 115 | 1999 |
| Discovery of a novel oral glucocorticoid receptor modulator (AZD9567) with improved side effect profile L Ripa, K Edman, M Dearman, G Edenro, R Hendrickx, V Ullah, ... Journal of Medicinal Chemistry 61 (5), 1785-1799, 2018 | 66 | 2018 |
| A new method for the reproducible generation of polymorphs: two forms of sulindac with very different solubilities A Llinas, KJ Box, JC Burley, RC Glen, JM Goodman Journal of Applied Crystallography 40 (2), 379-381, 2007 | 64 | 2007 |
| Solubility challenge revisited after ten years, with multilab shake-flask data, using tight (SD∼ 0.17 log) and loose (SD∼ 0.62 log) test sets A Llinas, A Avdeef Journal of Chemical Information and Modeling 59 (6), 3036-3040, 2019 | 51 | 2019 |
| Inhibitors of metallo-β-lactamase generated from β-lactam antibiotics A Badarau, A Llinįs, AP Laws, C Damblon, MI Page Biochemistry 44 (24), 8578-8589, 2005 | 49 | 2005 |
| Intramolecular general acid catalysis in the aminolysis of β-lactam antibiotics A Llinįs, MI Page Organic & Biomolecular Chemistry 2 (5), 651-654, 2004 | 48 | 2004 |
| Findings of the second challenge to predict aqueous solubility A Llinas, I Oprisiu, A Avdeef Journal of chemical information and modeling 60 (10), 4791-4803, 2020 | 47 | 2020 |
| Discovery of AZD6642, an inhibitor of 5-lipoxygenase activating protein (FLAP) for the treatment of inflammatory diseases M Lemurell, J Ulander, S Winiwarter, A Dahlen, O Davidsson, ... Journal of Medicinal Chemistry 58 (2), 897-911, 2015 | 39 | 2015 |
| Inactivation of Bacterial dd-Peptidase by β-Sultams A Llinįs, N Ahmed, M Cordaro, AP Laws, JM Frere, M Delmarcelle, ... Biochemistry 44 (21), 7738-7746, 2005 | 38 | 2005 |
| Concomitant hydrate polymorphism in the precipitation of sparfloxacin from aqueous solution A Llinąs, JC Burley, TJ Prior, RC Glen, JM Goodman Crystal Growth and Design 8 (1), 114-118, 2008 | 35 | 2008 |
| Potent and orally bioavailable inverse agonists of RORγt resulting from structure-based design F Narjes, Y Xue, S von Berg, J Malmberg, A Llinas, RI Olsson, J Jirholt, ... Journal of Medicinal Chemistry 61 (17), 7796-7813, 2018 | 31 | 2018 |
| Chemical reactivity of penicillins and cephalosporins. Intramolecular involvement of the acyl-amido side chain A Llinįs, B Vilanova, J Frau, F Munoz, J Donoso, MI Page The Journal of Organic Chemistry 63 (24), 9052-9060, 1998 | 31 | 1998 |
