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J Alex Parker
J Alex Parker
Professor - CRCHUM - Universite de Montreal
Dirección de correo verificada de umontreal.ca - Página principal
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Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons
JA Parker, M Arango, S Abderrahmane, E Lambert, C Tourette, H Catoire, ...
Nature genetics 37 (4), 349-350, 2005
6292005
SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis
R Luthi-Carter, DM Taylor, J Pallos, E Lambert, A Amore, A Parker, ...
Proceedings of the National Academy of Sciences 107 (17), 7927, 2010
3872010
C. elegans neurons jettison protein aggregates and mitochondria under neurotoxic stress
I Melentijevic, ML Toth, ML Arnold, RJ Guasp, G Harinath, KC Nguyen, ...
Nature 542 (7641), 367-371, 2017
3262017
Expanded polyglutamines in Caenorhabditis elegans cause axonal abnormalities and severe dysfunction of PLM mechanosensory neurons without cell death
JA Parker, JB Connolly, C Wellington, M Hayden, J Dausset, C Neri
Proceedings of the National Academy of Sciences 98 (23), 13318-13323, 2001
2852001
Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase
M Borrell-Pagès, JM Canals, FP Cordelières, JA Parker, JR Pineda, ...
The Journal of clinical investigation 116 (5), 1410-1424, 2006
2622006
Deletion of C9ORF72 results in motor neuron degeneration and stress sensitivity in C. elegans
M Therrien, GA Rouleau, PA Dion, JA Parker
PloS one 8 (12), e83450, 2013
2292013
Pharmacological reduction of ER stress protects against TDP-43 neuronal toxicity< i> in vivo</i>
A Vaccaro, SA Patten, D Aggad, C Julien, C Maios, E Kabashi, P Drapeau, ...
Neurobiology of Disease, 2013
1422013
Mutant TDP-43 and FUS cause age-dependent paralysis and neurodegeneration in C. elegans
A Vaccaro, A Tauffenberger, D Aggad, G Rouleau, P Drapeau, JA Parker
PloS one 7 (2), e31321, 2012
1372012
G3BP1 promotes stress-induced RNA granule interactions to preserve polyadenylated mRNA
A Aulas, G Caron, CG Gkogkas, NV Mohamed, L Destroismaisons, ...
Journal of Cell Biology 209 (1), 73-84, 2015
1242015
Mutations in CAPN1 cause autosomal-recessive hereditary spastic paraplegia
Z Gan-Or, N Bouslam, N Birouk, A Lissouba, DB Chambers, J Vérièpe, ...
The American Journal of Human Genetics 98 (5), 1038-1046, 2016
1152016
Methylene Blue Protects against TDP-43 and FUS Neuronal Toxicity in C. elegans and D. rerio
A Vaccaro, SA Patten, S Ciura, C Maios, M Therrien, P Drapeau, ...
PLoS ONE 7 (7), e42117, 2012
1122012
Restless legs syndrome‐associated MEIS1 risk variant influences iron homeostasis
H Catoire, PA Dion, L Xiong, M Amari, R Gaudet, SL Girard, A Noreau, ...
Annals of neurology 70 (1), 170-175, 2011
1022011
Sirtuin inhibition protects from the polyalanine muscular dystrophy protein PABPN1
H Catoire, MY Pasco, A Abu-Baker, S Holbert, C Tourette, B Brais, ...
Human molecular genetics 17 (14), 2108-2117, 2008
1002008
Pleiotropic effects of mTOR and autophagy during development and aging
K Schmeisser, JA Parker
Frontiers in cell and developmental biology 7, 192, 2019
972019
AMPK activation protects from neuronal dysfunction and vulnerability across nematode, cellular and mouse models of Huntington's disease
RP Vázquez-Manrique, F Farina, K Cambon, M Dolores Sequedo, ...
Human molecular genetics 25 (6), 1043-1058, 2016
972016
TDP-1/TDP-43 Regulates Stress Signaling and Age-Dependent Proteotoxicity in Caenorhabditis elegans
A Vaccaro, A Tauffenberger, PEA Ash, Y Carlomagno, L Petrucelli, ...
PLoS Genetics 8 (7), e1002806, 2012
952012
Neuroleptics as therapeutic compounds stabilizing neuromuscular transmission in amyotrophic lateral sclerosis
SA Patten, D Aggad, J Martinez, E Tremblay, J Petrillo, GAB Armstrong, ...
JCI insight 2 (22), 2017
912017
Equine stomachs harbor an abundant and diverse mucosal microbiota
GA Perkins, HC Den Bakker, AJ Burton, HN Erb, SP McDonough, ...
Applied and Environmental Microbiology 78 (8), 2522-2532, 2012
912012
Neurodegeneration in C. elegans models of ALS requires TIR-1/Sarm1 immune pathway activation in neurons
J Vérièpe, L Fossouo, JA Parker
Nature communications 6 (1), 7319, 2015
882015
Huntingtin-interacting protein 1 influences worm and mouse presynaptic function and protects Caenorhabditis elegans neurons against mutant polyglutamine toxicity
JA Parker, M Metzler, J Georgiou, M Mage, JC Roder, AM Rose, ...
Journal of Neuroscience 27 (41), 11056-11064, 2007
812007
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20