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Mary Elizabeth Patti
Mary Elizabeth Patti
Investigator, Joslin Diabetes Center; Associate Professor, Harvard Medical School
Dirección de correo verificada de joslin.harvard.edu
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Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
ME Patti, AJ Butte, S Crunkhorn, K Cusi, R Berria, S Kashyap, Y Miyazaki, ...
Proceedings of the National Academy of Sciences 100 (14), 8466-8471, 2003
24022003
Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene
E Araki, MA Lipes, ME Patti, JC Brüning, B Haag III, RS Johnson, ...
Nature 372 (6502), 186-190, 1994
17371994
Insulin resistance differentially affects the PI 3-kinase–and MAP kinase–mediated signaling in human muscle
K Cusi, K Maezono, A Osman, M Pendergrass, ME Patti, T Pratipanawatr, ...
The Journal of clinical investigation 105 (3), 311-320, 2000
15782000
Sexual differentiation, pregnancy, calorie restriction, and aging affect the adipocyte-specific secretory protein adiponectin
TP Combs, AH Berg, MW Rajala, S Klebanov, P Iyengar, ...
Diabetes 52 (2), 268-276, 2003
7262003
Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism
ME Patti, SM Houten, AC Bianco, R Bernier, PR Larsen, JJ Holst, ...
Obesity 17 (9), 1671-1677, 2009
6822009
In utero undernourishment perturbs the adult sperm methylome and intergenerational metabolism
EJ Radford, M Ito, H Shi, JA Corish, K Yamazawa, E Isganaitis, ...
Science 345 (6198), 1255903, 2014
6612014
The role of mitochondria in the pathogenesis of type 2 diabetes
ME Patti, S Corvera
Endocrine reviews 31 (3), 364-395, 2010
6492010
Bidirectional modulation of insulin action by amino acids.
ME Patti, E Brambilla, L Luzi, EJ Landaker, CR Kahn
The Journal of clinical investigation 101 (7), 1519-1529, 1998
6021998
Patients with neuroglycopenia after gastric bypass surgery have exaggerated incretin and insulin secretory responses to a mixed meal
AB Goldfine, EC Mun, E Devine, R Bernier, M Baz-Hecht, DB Jones, ...
The Journal of Clinical Endocrinology & Metabolism 92 (12), 4678-4685, 2007
4352007
Severe hypoglycaemia post-gastric bypass requiring partial pancreatectomy: evidence for inappropriate insulin secretion and pancreatic islet hyperplasia
ME Patti, G McMahon, EC Mun, A Bitton, JJ Holst, J Goldsmith, DW Hanto, ...
Diabetologia 48, 2236-2240, 2005
4072005
The emerging genetic architecture of type 2 diabetes
A Doria, ME Patti, CR Kahn
Cell metabolism 8 (3), 186-200, 2008
4032008
Intergenerational transmission of glucose intolerance and obesity by in utero undernutrition in mice
JC Jimenez-Chillaron, E Isganaitis, M Charalambous, S Gesta, ...
Diabetes 58 (2), 460-468, 2009
3642009
Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance of early postreceptor insulin signaling events in skeletal muscle.
ME Patti, A Virkamäki, EJ Landaker, CR Kahn, H Yki-Järvinen
Diabetes 48 (8), 1562-1571, 1999
3521999
Metabolic effects of sodium metavanadate in humans with insulin-dependent and noninsulin-dependent diabetes mellitus in vivo and in vitro studies
AB Goldfine, DC Simonson, F Folli, ME Patti, CR Kahn
The Journal of Clinical Endocrinology & Metabolism 80 (11), 3311-3320, 1995
3251995
4ps/insulin receptor substrate (irs)-2 is the alternative substrate of the insulin receptor in irs-1-deficient mice (∗)
ME Patti, XJ Sun, JC Bruening, E Araki, MA Lipes, MF White, CR Kahn
Journal of Biological Chemistry 270 (42), 24670-24673, 1995
3011995
Peroxisome proliferator activator receptor γ coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated …
S Crunkhorn, F Dearie, C Mantzoros, H Gami, WS da Silva, D Espinoza, ...
Journal of Biological Chemistry 282 (21), 15439-15450, 2007
2712007
Prediction of preadipocyte differentiation by gene expression reveals role of insulin receptor substrates and necdin
YH Tseng, AJ Butte, E Kokkotou, VK Yechoor, CM Taniguchi, ...
Nature cell biology 7 (6), 601-611, 2005
2712005
Metabolic effects of vanadyl sulfate in humans with non—insulin-dependent diabetes mellitus: in vivo and in vitro studies
AB Goldfine, ME Patti, L Zuberi, BJ Goldstein, R LeBlanc, EJ Landaker, ...
Metabolism 49 (3), 400-410, 2000
2572000
The insulin receptor-a critical link in glucose homeostasis and insulin action
ME Patti, CR Kahn
Journal of basic and clinical physiology and pharmacology 9 (2-4), 89-110, 1998
2261998
Epigenetic mechanisms of transmission of metabolic disease across generations
VM Sales, AC Ferguson-Smith, ME Patti
Cell metabolism 25 (3), 559-571, 2017
2242017
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Artículos 1–20