Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9 D Niu, HJ Wei, L Lin, H George, T Wang, IH Lee, HY Zhao, Y Wang, Y Kan, ... Science 357 (6357), 1303-1307, 2017 | 751 | 2017 |
Extensive germline genome engineering in pigs Y Yue, W Xu, Y Kan, HY Zhao, Y Zhou, X Song, J Wu, J Xiong, ... Nature Biomedical Engineering 5 (2), 134-143, 2021 | 139 | 2021 |
The HSV-1 exonuclease, UL12, stimulates recombination by a single strand annealing mechanism AJ Schumacher, KN Mohni, Y Kan, EA Hendrickson, JM Stark, SK Weller Public Library of Science 8 (8), e1002862, 2012 | 107 | 2012 |
Engineering and optimising deaminase fusions for genome editing L Yang, AW Briggs, WL Chew, P Mali, M Guell, J Aach, DB Goodman, ... Nature Communications 7 (1), 13330, 2016 | 104 | 2016 |
Mechanisms of precise genome editing using oligonucleotide donors Y Kan, B Ruis, T Takasugi, EA Hendrickson Genome research 27 (7), 1099-1111, 2017 | 103 | 2017 |
Kidney transplantation from triple‐knockout pigs expressing multiple human proteins in cynomolgus macaques D Ma, T Hirose, G Lassiter, H Sasaki, I Rosales, TM Coe, CG Rickert, ... American Journal of Transplantation 22 (1), 46-57, 2022 | 74 | 2022 |
The mechanism of gene targeting in human somatic cells Y Kan, B Ruis, S Lin, EA Hendrickson PLoS genetics 10 (4), e1004251, 2014 | 64 | 2014 |
The phosphorylation state of an aurora-like kinase marks the length of growing flagella in Chlamydomonas M Luo, M Cao, Y Kan, G Li, W Snell, J Pan Current Biology 21 (7), 586-591, 2011 | 51 | 2011 |
FANCI and FANCD2 have common as well as independent functions during the cellular replication stress response EL Thompson, JE Yeo, EA Lee, Y Kan, M Raghunandan, C Wiek, ... Nucleic acids research 45 (20), 11837-11857, 2017 | 44 | 2017 |
A ONE‐SHOT SOLUTION TO BACTERIAL AND FUNGAL CONTAMINATION IN THE GREEN ALGA CHLAMYDOMONAS REINHARDTII CULTURE BY USING AN ANTIBIOTIC … Y Kan, J Pan Journal of phycology 46 (6), 1356-1358, 2010 | 44 | 2010 |
PERV inactivation is necessary to guarantee absence of pig-to-patient PERVs transmission in xenotransplantation M Güell, D Niu, Y Kan, H George, T Wang, IH Lee, G Wang, G Church, ... Xenotransplantation 24 (6), e12366, 2017 | 36 | 2017 |
Human somatic cells deficient for RAD52 are impaired for viral integration and compromised for most aspects of homology-directed repair Y Kan, NN Batada, EA Hendrickson DNA repair 55, 64-75, 2017 | 33 | 2017 |
Design and testing of a humanized porcine donor for xenotransplantation RP Anand, JV Layer, D Heja, T Hirose, G Lassiter, DJ Firl, VB Paragas, ... Nature 622 (7982), 393-401, 2023 | 32 | 2023 |
A role for XLF in DNA repair and recombination in human somatic cells FJ Fattah, J Kweon, Y Wang, EH Lee, Y Kan, N Lichter, N Weisensel, ... DNA repair 15, 39-53, 2014 | 27 | 2014 |
DNA Ligase 1 is an essential mediator of sister chromatid telomere fusions in G2 cell cycle phase K Liddiard, B Ruis, Y Kan, K Cleal, KE Ashelford, EA Hendrickson, ... Nucleic acids research 47 (5), 2402-2424, 2019 | 23 | 2019 |
Extensive mammalian germline genome engineering Y Yue, Y Kan, W Xu, HY Zhao, Y Zhou, X Song, J Wu, J Xiong, ... BioRxiv, 2019.12. 17.876862, 2019 | 13 | 2019 |
Successful long-term TMA-and rejection-free survival of a kidney xenograft with triple xenoantigen knockout plus insertion of multiple human transgenes D Ma, T Hirose, I Rosales, H Sasaki, R Colvin, J Markmann, W Qin, Y Kan, ... Transplantation 104 (S3), S82, 2020 | 4 | 2020 |
Genetic modifications designed for xenotransplantation attenuate sialoadhesin‐dependent binding of human erythrocytes to porcine macrophages K Petitpas, Z Habibabady, V Ritchie, MR Connolly, L Burdorf, W Qin, ... Xenotransplantation 29 (6), e12780, 2022 | 3 | 2022 |
Conversion tract analysis of homology-directed genome editing using oligonucleotide donors Y Kan, EA Hendrickson DNA Repair: Methods and Protocols, 131-144, 2019 | 3 | 2019 |
Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9 D Niu, HJ Wei, L Lin, H George, T Wang, IH Lee, HY Zhao, Y Wang, Y Kan, ... Transgenic Research 27 (5), 483-483, 2018 | 3 | 2018 |