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Mariela Sivina, PhD
Mariela Sivina, PhD
Dirección de correo verificada de mdanderson.org
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The phosphoinositide 3′-kinase delta inhibitor, CAL-101, inhibits B-cell receptor signaling and chemokine networks in chronic lymphocytic leukemia
J Hoellenriegel, SA Meadows, M Sivina, WG Wierda, H Kantarjian, ...
Blood, The Journal of the American Society of Hematology 118 (13), 3603-3612, 2011
6652011
Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion …
AV Kurtova, K Balakrishnan, R Chen, W Ding, S Schnabl, MP Quiroga, ...
Blood, The Journal of the American Society of Hematology 114 (20), 4441-4450, 2009
4222009
Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition
JA Burger, DA Landau, A Taylor-Weiner, I Bozic, H Zhang, K Sarosiek, ...
Nature communications 7 (1), 11589, 2016
3702016
B-cell antigen receptor signaling enhances chronic lymphocytic leukemia cell migration and survival: specific targeting with a novel spleen tyrosine kinase inhibitor, R406
MP Quiroga, K Balakrishnan, AV Kurtova, M Sivina, MJ Keating, ...
Blood, The Journal of the American Society of Hematology 114 (5), 1029-1037, 2009
3112009
Randomized trial of ibrutinib vs ibrutinib plus rituximab in patients with chronic lymphocytic leukemia
JA Burger, M Sivina, N Jain, E Kim, T Kadia, Z Estrov, ...
Blood, The Journal of the American Society of Hematology 133 (10), 1011-1019, 2019
2382019
Lenalidomide as initial therapy of elderly patients with chronic lymphocytic leukemia
XC Badoux, MJ Keating, S Wen, BN Lee, M Sivina, J Reuben, WG Wierda, ...
Blood, The Journal of the American Society of Hematology 118 (13), 3489-3498, 2011
2202011
The transcription factor MEF/ELF4 regulates the quiescence of primitive hematopoietic cells
HD Lacorazza, T Yamada, Y Liu, Y Miyata, M Sivina, J Nunes, SD Nimer
Cancer cell 9 (3), 175-187, 2006
1942006
The evolutionary landscape of chronic lymphocytic leukemia treated with ibrutinib targeted therapy
DA Landau, C Sun, D Rosebrock, SEM Herman, J Fein, M Sivina, ...
Nature communications 8 (1), 2185, 2017
1752017
Selective, novel spleen tyrosine kinase (Syk) inhibitors suppress chronic lymphocytic leukemia B-cell activation and migration
J Hoellenriegel, GP Coffey, U Sinha, A Pandey, M Sivina, A Ferrajoli, ...
Leukemia 26 (7), 1576-1583, 2012
1632012
CCL3 (MIP-1α) plasma levels and the risk for disease progression in chronic lymphocytic leukemia
M Sivina, E Hartmann, TJ Kipps, L Rassenti, D Krupnik, S Lerner, ...
Blood, The Journal of the American Society of Hematology 117 (5), 1662-1669, 2011
1472011
Ibrutinib therapy increases T cell repertoire diversity in patients with chronic lymphocytic leukemia
Q Yin, M Sivina, H Robins, E Yusko, M Vignali, S O’Brien, MJ Keating, ...
The Journal of Immunology 198 (4), 1740-1747, 2017
1232017
The PI3-kinase delta inhibitor idelalisib (GS-1101) targets integrin-mediated adhesion of chronic lymphocytic leukemia (CLL) cell to endothelial and marrow stromal cells
S Fiorcari, WS Brown, BW McIntyre, Z Estrov, R Maffei, S O’Brien, ...
PloS one 8 (12), e83830, 2013
1082013
Leukemia cell proliferation and death in chronic lymphocytic leukemia patients on therapy with the BTK inhibitor ibrutinib
JA Burger, KW Li, MJ Keating, M Sivina, AM Amer, N Garg, A Ferrajoli, ...
JCI insight 2 (2), 2017
982017
The bruton tyrosine kinase inhibitor ibrutinib (PCI‐32765) blocks hairy cell leukaemia survival, proliferation and B cell receptor signalling: a new therapeutic approach
M Sivina, RJ Kreitman, E Arons, F Ravandi, JA Burger
British journal of haematology 166 (2), 177-188, 2014
702014
The bruton tyrosine kinase inhibitor ibrutinib (PCI‐32765) blocks hairy cell leukaemia survival, proliferation and B cell receptor signalling: a new therapeutic approach
M Sivina, RJ Kreitman, E Arons, F Ravandi, JA Burger
British journal of haematology 166 (2), 177-188, 2014
702014
Molecular map of chronic lymphocytic leukemia and its impact on outcome
BA Knisbacher, Z Lin, CK Hahn, F Nadeu, M Duran-Ferrer, KE Stevenson, ...
Nature genetics 54 (11), 1664-1674, 2022
662022
CCL 3 and CCL 4 are biomarkers for B cell receptor pathway activation and prognostic serum markers in diffuse large B cell lymphoma
K Takahashi, M Sivina, J Hoellenriegel, Y Oki, FB Hagemeister, L Fayad, ...
British journal of haematology 171 (5), 726-735, 2015
642015
Long-term follow-up of treatment with ibrutinib and rituximab in patients with high-risk chronic lymphocytic leukemia
P Jain, MJ Keating, WG Wierda, M Sivina, PA Thompson, A Ferrajoli, ...
Clinical Cancer Research 23 (9), 2154-2158, 2017
582017
Stromal cells modulate TCL1 expression, interacting AP-1 components and TCL1-targeting micro-RNAs in chronic lymphocytic leukemia
M Sivina, E Hartmann, E Vasyutina, JM Boucas, A Breuer, MJ Keating, ...
Leukemia 26 (8), 1812-1820, 2012
522012
Autoimmune cytopenias in patients with chronic lymphocytic leukemia treated with ibrutinib
C Vitale, IE Ahn, M Sivina, A Ferrajoli, WG Wierda, Z Estrov, SN Konoplev, ...
Haematologica 101 (6), e254, 2016
492016
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