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Raphael Pavani
Raphael Pavani
Laboratory of Genome Integrity/NCI/NIH
Dirección de correo verificada de nih.gov
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Neuronal enhancers are hotspots for DNA single-strand break repair
W Wu, SE Hill, WJ Nathan, J Paiano, E Callen, D Wang, K Shinoda, ...
Nature 593, 440–444, 2021
1402021
53BP1 enforces distinct pre-and post-resection blocks on homologous recombination
E Callen, D Zong, W Wu, N Wong, A Stanlie, M Ishikawa, R Pavani, ...
Molecular cell 77 (1), 26-38, 2020
992020
Active DNA demethylation promotes cell fate specification and the DNA damage response
D Wang, W Wu, E Callen, R Pavani, N Zolnerowich, S Kodali, D Zong, ...
Science 378 (6623), 983-989, 2022
422022
Nuclear DNA replication in trypanosomatids: there are no easy methods for solving difficult problems
MS da Silva, RS Pavani, JD Damasceno, CA Marques, R McCulloch, ...
Trends in parasitology 33 (11), 858-874, 2017
422017
CTCF is a barrier for 2C-like reprogramming
T Olbrich, M Vega-Sendino, D Tillo, W Wu, N Zolnerowich, R Pavani, ...
Nature Communications 12 (1), 4856, 2021
412021
Consequences of acute oxidative stress in Leishmania amazonensis: from telomere shortening to the selection of the fittest parasites
MS da Silva, M Segatto, RS Pavani, F Gutierrez-Rodrigues, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1864 (1), 138-150, 2017
362017
Replication Protein A Presents Canonical Functions and Is Also Involved in the Differentiation Capacity of Trypanosoma cruzi
RS Pavani, MS da Silva, CAH Fernandes, FS Morini, CB Araujo, ...
PLoS Neglected Tropical Diseases 10 (12), e0005181, 2016
342016
Role of 53BP1 in end protection and DNA synthesis at DNA breaks
J Paiano, N Zolnerowich, W Wu, R Pavani, C Wang, H Li, L Zheng, ...
Genes & development 35 (19-20), 1356-1367, 2021
332021
The glutamine synthetase of Trypanosoma cruzi is required for its resistance to ammonium accumulation and evasion of the parasitophorous vacuole during host …
M Crispim, FS Damasceno, A Hernández, MJ Barisón, I Pretto Sauter, ...
PLoS neglected tropical diseases 12 (1), e0006170, 2018
292018
Glyceraldehyde 3-Phosphate Dehydrogenase-Telomere Association Correlates with Redox Status in Trypanosoma cruzi
R Pariona-Llanos, RS Pavani, M Reis, V Noel, AM Silber, HA Armelin, ...
Plos one 10 (3), e0120896, 2015
282015
Recruitment kinetics of the homologous recombination pathway in procyclic forms of Trypanosoma brucei after ionizing radiation treatment
PA Marin, MS da Silva, RS Pavani, CR Machado, MC Elias
Scientific Reports 8 (1), 5405, 2018
252018
RPA-1 from Leishmania amazonensis (LaRPA-1) structurally differs from other eukaryote RPA-1 and interacts with telomeric DNA via its N-terminal OB-fold domain
RS Pavani, C Fernandes, AM Perez, EJR Vasconcelos, JL Siqueira-Neto, ...
FEBS letters 588 (24), 4740-4748, 2014
222014
S1-END-seq reveals DNA secondary structures in human cells
G Matos-Rodrigues, N van Wietmarschen, W Wu, V Tripathi, NC Koussa, ...
Molecular cell 82 (19), 3538-3552. e5, 2022
152022
Replication Protein A‐1 Has a Preference for the Telomeric G‐rich Sequence in Trypanosoma cruzi
RS Pavani, MO Vitarelli, CAH Fernandes, FF Mattioli, M Morone, ...
journal of eukaryotic microbiology 65 (3), 345-356, 2018
122018
ATR Kinase Is a Crucial Player Mediating the DNA Damage Response in Trypanosoma brucei
PA Marin, R Obonaga, RS Pavani, MS Da Silva, CB De Araujo, AA Lima, ...
Frontiers in cell and developmental biology 8, 602956, 2020
102020
DNA-PK promotes DNA end resection at DNA double strand breaks in G0 cells
FC Fowler, BR Chen, N Zolnerowich, W Wu, R Pavani, J Paiano, C Peart, ...
Elife 11, e74700, 2022
92022
Nuclear export of replication protein A in the nonreplicative infective forms of Trypanosoma cruzi
RS Pavani, LP de Lima, AA Lima, CAH Fernandes, SP Fragoso, ...
FEBS letters 594 (10), 1596–1607, 2020
72020
Following Trypanosoma cruzi RPA-DNA Interaction Using Fluorescent In Situ Hybridization Coupled with Immunofluorescence (FISH/IF).
RS Pavani, MC Elias
Methods in Molecular Biology (Clifton, NJ) 2281, 209-215, 2021
22021
EXO1 protects BRCA1-deficient cells against toxic DNA lesions
B van de Kooij, A Schreuder, R Pavani, V Garzero, S Uruci, TJ Wendel, ...
Molecular Cell 84 (4), 659-674. e7, 2024
12024
EXO1-mediated DNA repair by single-strand annealing is essential for BRCA1-deficient cells
B van de Kooij, A Schreuder, RS Pavani, V Garzero, A Van Hoeck, ...
bioRxiv, 2023.02. 24.529205, 2023
12023
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