Butelase 1 is an Asx-specific ligase enabling peptide macrocyclization and synthesis GKT Nguyen, S Wang, Y Qiu, X Hemu, Y Lian, JP Tam Nature chemical biology 10 (9), 732-738, 2014 | 442 | 2014 |
Butelase-mediated cyclization and ligation of peptides and proteins GKT Nguyen, Y Qiu, Y Cao, X Hemu, CF Liu, JP Tam Nature protocols 11 (10), 1977-1988, 2016 | 135 | 2016 |
Self-powered, on-demand transdermal drug delivery system driven by triboelectric nanogenerator Q Ouyang, X Feng, S Kuang, N Panwar, P Song, C Yang, G Yang, ... Nano Energy 62, 610-619, 2019 | 111 | 2019 |
Total synthesis of circular bacteriocins by butelase 1 X Hemu, Y Qiu, GKT Nguyen, JP Tam Journal of the American Chemical Society 138 (22), 6968-6971, 2016 | 111 | 2016 |
Butelase‐Mediated Macrocyclization of d‐Amino‐Acid‐Containing Peptides GKT Nguyen, X Hemu, JP Quek, JP Tam Angewandte Chemie 128 (41), 12994-12998, 2016 | 99 | 2016 |
Structural determinants for peptide-bond formation by asparaginyl ligases X Hemu, A El Sahili, S Hu, K Wong, Y Chen, YH Wong, X Zhang, A Serra, ... Proceedings of the National Academy of Sciences 116 (24), 11737-11746, 2019 | 93 | 2019 |
Enzymatic engineering of live bacterial cell surfaces using butelase 1 X Bi, J Yin, GKT Nguyen, C Rao, NBA Halim, X Hemu, JP Tam, CF Liu Angewandte Chemie International Edition 56 (27), 7822-7825, 2017 | 89 | 2017 |
A thioethylalkylamido (TEA) thioester surrogate in the synthesis of a cyclic peptide via a tandem acyl shift M Taichi, X Hemu, Y Qiu, JP Tam Organic letters 15 (11), 2620-2623, 2013 | 65 | 2013 |
A high-throughput peptidomic strategy to decipher the molecular diversity of cyclic cysteine-rich peptides A Serra, X Hemu, GKT Nguyen, NTK Nguyen, SK Sze, JP Tam Scientific Reports 6 (1), 23005, 2016 | 58 | 2016 |
Biomimetic synthesis of cyclic peptides using novel thioester surrogates X Hemu, M Taichi, Y Qiu, DX Liu, JP Tam Peptide Science 100 (5), 492-501, 2013 | 42 | 2013 |
Turning an asparaginyl endopeptidase into a peptide ligase X Hemu, A El Sahili, S Hu, X Zhang, A Serra, BC Goh, DA Darwis, ... ACS catalysis 10 (15), 8825-8834, 2020 | 35 | 2020 |
Immobilization and intracellular delivery of circular proteins by modifying a genetically incorporated unnatural amino acid X Bi, J Yin, X Hemu, C Rao, JP Tam, CF Liu Bioconjugate chemistry 29 (7), 2170-2175, 2018 | 28 | 2018 |
Commercial processed soy-based food product contains glycated and glycoxidated lunasin proteoforms A Serra, X Gallart-Palau, RSE See-Toh, X Hemu, JP Tam, SK Sze Scientific reports 6 (1), 26106, 2016 | 28 | 2016 |
Immobilized peptide asparaginyl ligases enhance stability and facilitate macrocyclization and site-specific ligation X Hemu, J To, X Zhang, JP Tam The Journal of Organic Chemistry 85 (3), 1504-1512, 2019 | 24 | 2019 |
Engineering protein theranostics using bio-orthogonal asparaginyl peptide ligases Z Wang, D Zhang, X Hemu, S Hu, J To, X Zhang, J Lescar, JP Tam, CF Liu Theranostics 11 (12), 5863, 2021 | 21 | 2021 |
Macrocyclic antimicrobial peptides engineered from ω-conotoxin X Hemu, J P Tam Current pharmaceutical design 23 (14), 2131-2138, 2017 | 21 | 2017 |
Characterization and application of natural and recombinant butelase-1 to improve industrial enzymes by end-to-end circularization X Hemu, X Zhang, GKT Nguyen, J To, A Serra, S Loo, SK Sze, CF Liu, ... RSC advances 11 (37), 23105-23112, 2021 | 18 | 2021 |
Ligase-controlled cyclo-oligomerization of peptides X Hemu, X Zhang, JP Tam Organic letters 21 (7), 2029-2032, 2019 | 17 | 2019 |
Butelase 1-mediated ligation of peptides and proteins X Hemu, X Zhang, X Bi, CF Liu, JP Tam Enzyme-mediated ligation methods, 83-109, 2019 | 14 | 2019 |
Peptide macrocyclization through amide-to-amide transpeptidation X Hemu, Y Qiu, JP Tam Tetrahedron 70 (42), 7707-7713, 2014 | 12 | 2014 |