| SIRT1 controls acetaminophen hepatotoxicity by modulating inflammation and oxidative stress P Rada, V Pardo, MA Mobasher, I García-Martínez, L Ruiz, ... Antioxidants & redox signaling 28 (13), 1187-1208, 2018 | 108 | 2018 |
| Exploiting oxidative phosphorylation to promote the stem and immunoevasive properties of pancreatic cancer stem cells S Valle, S Alcalá, L Martin-Hijano, P Cabezas-Sáinz, D Navarro, ... Nature Communications 11 (1), 5265, 2020 | 89 | 2020 |
| A novel glucagon‐like peptide 1/glucagon receptor dual agonist improves steatohepatitis and liver regeneration in mice MP Valdecantos, V Pardo, L Ruiz, L Castro‐Sánchez, B Lanzón, ... Hepatology 65 (3), 950-968, 2017 | 84 | 2017 |
| ISG15 and ISGylation is required for pancreatic cancer stem cell mitophagy and metabolic plasticity S Alcalá, P Sancho, P Martinelli, D Navarro, C Pedrero, L Martín-Hijano, ... Nature communications 11 (1), 2682, 2020 | 77 | 2020 |
| Macrophages direct cancer cells through a LOXL2-mediated metastatic cascade in pancreatic ductal adenocarcinoma M Alonso-Nocelo, L Ruiz-Cañas, P Sancho, K Görgülü, S Alcalá, ... Gut 72 (2), 345-359, 2023 | 26 | 2023 |
| Targeting SRC Kinase Signaling in Pancreatic Cancer Stem Cells S Alcalá, V Mayoral-Varo, L Ruiz-Cañas, JC López-Gil, C Heeschen, ... International journal of molecular sciences 21 (20), 7437, 2020 | 23 | 2020 |
| Extensive preclinical validation of combined RMC-4550 and LY3214996 supports clinical investigation for KRAS mutant pancreatic cancer KJ Frank, A Mulero-Sanchez, A Berninger, L Ruiz-Canas, A Bosma, ... Cell Reports Medicine 3 (11), 2022 | 21 | 2022 |
| Protein tyrosine phosphatase 1b deficiency protects against hepatic fibrosis by modulating nadph oxidases I García-Ruiz, NB Ruiz, P Rada, V Pardo, L Ruiz, A Blas-García, ... Redox biology 26, 101263, 2019 | 21 | 2019 |
| Establishment of Pancreatic Cancer-Derived Tumor Organoids and Fibroblasts From Fresh Tissue JF Díaz-Alejo, S April-Monn, M Cihova, V Buocikova, JV López, ... JoVE (Journal of Visualized Experiments), e65229, 2023 | 2 | 2023 |
| Targeting cancer stem cell OXPHOS with tailored ruthenium complexes as a new anti-cancer strategy S Alcalá, L Villarino, L Ruiz-Cañas, JR Couceiro, M Martínez-Calvo, ... Journal of Experimental & Clinical Cancer Research 43 (1), 33, 2024 | 1 | 2024 |
| Platinum iodido drugs show potential anti-tumor activity, affecting cancer cell metabolism and inducing ROS and senescence in gastrointestinal cancer cells J Melones-Herrero, S Alcalá, L Ruiz-Cañas, C Benítez-Buelga, ... Communications Biology 7 (1), 353, 2024 | | 2024 |
| Abstract C079: Targeting cancer stem cell OXPHOS with tailored ruthenium complexes as a new approach to treat pancreatic cancer BJ Sainz, S Alcalá, L Villarino, L Ruíz-Cañas, J Couceiro, ... Cancer Research 84 (2_Supplement), C079-C079, 2024 | | 2024 |
| Aurora-Kinase-A-Inhibition als vielversprechende Therapiestrategie in ARID1A-mutierten Neuroendokrinen Karzinomen: Erste Ergebnisse einer in vitro und in vivo Studie F Viol, T Amin, B Sipos, T Fründt, M Fahl, B Smolkova, B Sainz, J Earl, ... Zeitschrift für Gastroenterologie 61 (08), KV255, 2023 | | 2023 |
| An Aptamer against MNK1 for Non-Small Cell Lung Cancer Treatment R Carrión-Marchante, C Pinto-Díez, JI Klett-Mingo, E Palacios, ... Pharmaceutics 15 (4), 1273, 2023 | | 2023 |
| PPAR-delta acts as a metabolic master checkpoint for metastasis in pancreatic cancer B Parejo-Alonso, D Barneda, S Trabulo, S Courtois, S Compte-Sancerni, ... bioRxiv, 2021.11. 15.468579, 2021 | | 2021 |
| Tailored ruthenium complexes target pancreatic cancer stem cells through inhibition of mitochondrial DNA transcription B Sainz Jr, S Alcala, JR Couceiro, L Ruiz-Cañas, M Martínez-Calvo, ... Pancreatology 21, S15, 2021 | | 2021 |
| Modulation of SIRT1 by IL1b/NFkB signaling during acetaminophen-induced hepatotoxicity P Rada, V Pardo, MA Mobasher, I García Martínez, L Ruiz-Cañas, ... | | 2018 |
| Regulacion de la homeostasis glucémica y del metabolismo lipídico por el factor de transcripción ALX3 L Ruiz Cañas Regulacion de la homeostasis glucémica y del metabolismo lipídico por el …, 2017 | | 2017 |
| Differential efficacy of a GLP-1R/GCGR agonist versus a GLP-1R agonist in improving hepatic insulin sensitivity and reducing steatosis in obese mice P Valdecantos, L Ruiz-Canas, P Rada, A Gonzalez-Rodrignez, A Konkar, ... DIABETOLOGIA 59, S374-S374, 2016 | | 2016 |
