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Jukka Holappa
Jukka Holappa
Owner Kasve Ltd Owner of HealthTradeCenter Ltd
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Antibacterial activity of methylated chitosan and chitooligomer derivatives: Synthesis and structure activity relationships
ÖV Rúnarsson, J Holappa, T Nevalainen, M Hjálmarsdóttir, T Järvinen, ...
European Polymer Journal 43 (6), 2660-2671, 2007
1952007
Antimicrobial activity of chitosan N-betainates
J Holappa, M Hjálmarsdóttir, M Másson, Ö Rúnarsson, T Asplund, ...
Carbohydrate Polymers 65 (1), 114-118, 2006
1592006
Synthesis and characterization of chitosan N-betainates having various degrees of substitution
J Holappa, T Nevalainen, J Savolainen, P Soininen, M Elomaa, R Safin, ...
Macromolecules 37 (8), 2784-2789, 2004
1302004
Antibacterial activity of N-quaternary chitosan derivatives: Synthesis, characterization and structure activity relationship (SAR) investigations
ÖV Rúnarsson, J Holappa, C Malainer, H Steinsson, M Hjálmarsdóttir, ...
European Polymer Journal 46 (6), 1251-1267, 2010
1262010
Antimicrobial activity of piperazine derivatives of chitosan
M Másson, J Holappa, M Hjálmarsdóttir, ÖV Rúnarsson, T Nevalainen, ...
Carbohydrate polymers 74 (3), 566-571, 2008
1222008
N-selective ‘one pot’synthesis of highly N-substituted trimethyl chitosan (TMC)
ÖV Rúnarsson, J Holappa, S Jónsdóttir, H Steinsson, M Másson
Carbohydrate polymers 74 (3), 740-744, 2008
792008
tert-Butyldimethylsilyl O-protected chitosan and chitooligosaccharides: Useful precursors for N-modifications in common organic solvents
ÖV Rúnarsson, C Malainer, J Holappa, ST Sigurdsson, M Másson
Carbohydrate research 343 (15), 2576-2582, 2008
682008
Synthesis of novel quaternary chitosan derivatives via N-chloroacyl-6-O-triphenylmethylchitosans
J Holappa, T Nevalainen, P Soininen, M Másson, T Järvinen
Biomacromolecules 7 (2), 407-410, 2006
582006
N-Chloroacyl-6-O-triphenylmethylchitosans:  Useful Intermediates for Synthetic Modifications of Chitosan
J Holappa, T Nevalainen, P Soininen, M Elomaa, R Safin, M Másson, ...
Biomacromolecules 6 (2), 858-863, 2005
512005
Novel Water‐Soluble Quaternary Piperazine Derivatives of Chitosan: Synthesis and Characterization
J Holappa, T Nevalainen, R Safin, P Soininen, T Asplund, T Luttikhedde, ...
Macromolecular bioscience 6 (2), 139-144, 2006
462006
Cyclodextrins and chitosan derivatives in sublingual delivery of low solubility peptides: A study using cyclosporin A, α-cyclodextrin and quaternary chitosan N-betainate
J Mannila, K Järvinen, J Holappa, L Matilainen, S Auriola, P Jarho
International journal of pharmaceutics 381 (1), 19-24, 2009
312009
Effect of N-betainate and N-piperazine derivatives of chitosan on the paracellular transport of mannitol in Caco-2 cells
T Korjamo, J Holappa, S Taimisto, J Savolainen, T Järvinen, J Mönkkönen
european journal of pharmaceutical sciences 35 (3), 226-234, 2008
102008
Quaternary polymers
J Holappa, T Järvinen, T Nevalainen, J Savolainen, R Safin
US Patent 7,838,643, 2010
42010
A novel and selective synthesis of di-and trimethylpiperazinium acetic acid iodide salts
J Holappa, T Nevalainen, R Safin, J Vepsäläinen, T Järvinen
Tetrahedron letters 47 (3), 323-325, 2006
42006
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