A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis LH Barbeito, M Pehar, P Cassina, MR Vargas, H Peluffo, L Viera, ... Brain research reviews 47 (1-3), 263-274, 2004 | 443 | 2004 |
NLRP3 inflammasome-driven pathways in depression: clinical and preclinical findings FN Kaufmann, AP Costa, G Ghisleni, AP Diaz, ALS Rodrigues, H Peluffo, ... Brain, behavior, and immunity 64, 367-383, 2017 | 362 | 2017 |
Peroxynitrite triggers a phenotypic transformation in spinal cord astrocytes that induces motor neuron apoptosis P Cassina, H Peluffo, M Pehar, L Martinez‐Palma, A Ressia, JS Beckman, ... Journal of neuroscience research 67 (1), 21-29, 2002 | 252 | 2002 |
Extracellular ATP and the P2X7receptor in astrocyte-mediated motor neuron death: implications for amyotrophic lateral sclerosis M Gandelman, H Peluffo, JS Beckman, P Cassina, L Barbeito Journal of neuroinflammation 7, 1-9, 2010 | 170 | 2010 |
BBB-targeting, protein-based nanomedicines for drug and nucleic acid delivery to the CNS H Peluffo, U Unzueta, ML Negro-Demontel, Z Xu, E Váquez, ... Biotechnology advances 33 (2), 277-287, 2015 | 99 | 2015 |
Induction of motor neuron apoptosis by free 3‐nitro‐l‐tyrosine H Peluffo, JJ Shacka, K Ricart, CG Bisig, L Martìnez‐Palma, O Pritsch, ... Journal of neurochemistry 89 (3), 602-612, 2004 | 76 | 2004 |
Riluzole promotes survival of rat motoneurons in vitro by stimulating trophic activity produced by spinal astrocyte monolayers H Peluffo, A Estevez, L Barbeito, JM Stutzmann Neuroscience letters 228 (3), 207-211, 1997 | 70 | 1997 |
Cu/Zn superoxide dismutase expression in the postnatal rat brain following an excitotoxic injury H Peluffo, L Acarin, M Faiz, B Castellano, B Gonzalez Journal of Neuroinflammation 2, 1-13, 2005 | 60 | 2005 |
Expression of inducible nitric oxide synthase and cyclooxygenase‐2 after excitotoxic damage to the immature rat brain L Acarin, H Peluffo, B González, B Castellano Journal of neuroscience research 68 (6), 745-754, 2002 | 60 | 2002 |
Interleukin-10 and Interleukin Refeceptor-I Are Upregulated in Glial Cells After an Excitotoxic Injury to the Postnatal Rat Brain P Gonzalez, F Burgaya, L Acarin, H Peluffo, B Castellano, B Gonzalez Journal of Neuropathology & Experimental Neurology 68 (4), 391-403, 2009 | 59 | 2009 |
CD300f immunoreceptor contributes to peripheral nerve regeneration by the modulation of macrophage inflammatory phenotype H Peluffo, P Solari-Saquieres, ML Negro-Demontel, I Francos-Quijorna, ... Journal of neuroinflammation 12, 1-15, 2015 | 52 | 2015 |
Efficient gene expression from integration-deficient lentiviral vectors in the spinal cord H Peluffo, E Foster, SG Ahmed, N Lago, TH Hutson, L Moon, P Yip, ... Gene therapy 20 (6), 645-657, 2013 | 51 | 2013 |
Neuroprotection from NMDA excitotoxic lesion by Cu/Zn superoxide dismutase gene delivery to the postnatal rat brain by a modular protein vector H Peluffo, L Acarin, A Arís, P González, A Villaverde, B Castellano, ... BMC neuroscience 7, 1-11, 2006 | 44 | 2006 |
Astroglial nitration after postnatal excitotoxic damage: correlation with nitric oxide sources, cytoskeletal, apoptotic and antioxidant proteins L Acarin, H Peluffo, L Barbeito, B Castellano, B González Journal of neurotrauma 22 (1), 189-200, 2005 | 42 | 2005 |
CD200 modulates spinal cord injury neuroinflammation and outcome through CD200R1 N Lago, B Pannunzio, J Amo-Aparicio, R López-Vales, H Peluffo Brain, behavior, and immunity 73, 416-426, 2018 | 40 | 2018 |
Overexpression of the immunoreceptor CD300f has a neuroprotective role in a model of acute brain injury H Peluffo, D Alí‐Ruiz, A Ejarque‐Ortíz, V Heras‐Alvarez, ... Brain Pathology 22 (3), 318-328, 2012 | 38 | 2012 |
CD300f immunoreceptor is associated with major depressive disorder and decreased microglial metabolic fitness N Lago, FN Kaufmann, ML Negro-Demontel, D Alí-Ruiz, G Ghisleni, ... Proceedings of the National Academy of Sciences 117 (12), 6651-6662, 2020 | 31 | 2020 |
Nonviral gene delivery to the central nervous system based on a novel integrin-targeting multifunctional protein H Peluffo, A Aris, L Acarin, B Gonzalez, A Villaverde, B Castellano Human gene therapy 14 (13), 1215-1223, 2003 | 29 | 2003 |
RGD-based cell ligands for cell-targeted drug delivery act as potent trophic factors J Domingo-Espín, V Petegnief, N de Vera, O Conchillo-Solé, P Saccardo, ... Nanomedicine: Nanotechnology, Biology and Medicine 8 (8), 1263-1266, 2012 | 28 | 2012 |
RGD domains neuroprotect the immature brain by a glial‐dependent mechanism H Peluffo, P González, A Arís, L Acarin, J Saura, A Villaverde, ... Annals of Neurology: Official Journal of the American Neurological …, 2007 | 28 | 2007 |