Lactate racemase is a nickel-dependent enzyme activated by a widespread maturation system B Desguin, P Goffin, E Viaene, M Kleerebezem, V Martin-Diaconescu, ... Nature communications 5 (1), 3615, 2014 | 114 | 2014 |
A tethered niacin-derived pincer complex with a nickel-carbon bond in lactate racemase B Desguin, T Zhang, P Soumillion, P Hols, J Hu, RP Hausinger Science 349 (6243), 66-69, 2015 | 98 | 2015 |
Channel-mediated lactic acid transport: a novel function for aquaglyceroporins in bacteria GP Bienert, B Desguin, F Chaumont, P Hols Biochemical Journal 454 (3), 559-570, 2013 | 97 | 2013 |
Nickel-pincer cofactor biosynthesis involves LarB-catalyzed pyridinium carboxylation and LarE-dependent sacrificial sulfur insertion B Desguin, P Soumillion, P Hols, RP Hausinger Proceedings of the National Academy of Sciences 113 (20), 5598-5603, 2016 | 48 | 2016 |
Biosynthesis of the nickel-pincer nucleotide cofactor of lactate racemase requires a CTP-dependent cyclometallase B Desguin, M Fellner, O Riant, J Hu, RP Hausinger, P Hols, P Soumillion Journal of Biological Chemistry 293 (32), 12303-12317, 2018 | 41 | 2018 |
Structural insights into the catalytic mechanism of a sacrificial sulfur insertase of the N-type ATP pyrophosphatase family, LarE M Fellner, B Desguin, RP Hausinger, J Hu Proceedings of the National Academy of Sciences 114 (34), 9074-9079, 2017 | 38 | 2017 |
Lactate racemase nickel-pincer cofactor operates by a proton-coupled hydride transfer mechanism JA Rankin, RC Mauban, M Fellner, B Desguin, J McCracken, J Hu, ... Biochemistry 57 (23), 3244-3251, 2018 | 30 | 2018 |
Enantioselective regulation of lactate racemization by LarR in Lactobacillus plantarum B Desguin, P Goffin, N Bakouche, A Diman, E Viaene, D Dandoy, ... Journal of bacteriology 197 (1), 219-230, 2015 | 26 | 2015 |
Unexpected complexity in the lactate racemization system of lactic acid bacteria B Desguin, P Soumillion, RP Hausinger, P Hols FEMS Microbiology Reviews 41 (Supp_1), S71-S83, 2017 | 23 | 2017 |
Uncovering a superfamily of nickel-dependent hydroxyacid racemases and epimerases B Desguin, J Urdiain-Arraiza, M Da Costa, M Fellner, J Hu, RP Hausinger, ... Scientific reports 10 (1), 18123, 2020 | 19 | 2020 |
Analysis of the Active Site Cysteine Residue of the Sacrificial Sulfur Insertase LarE from Lactobacillus plantarum M Fellner, JA Rankin, B Desguin, J Hu, RP Hausinger Biochemistry 57 (38), 5513-5523, 2018 | 18 | 2018 |
Nickel–pincer nucleotide cofactor RP Hausinger, B Desguin, M Fellner, JA Rankin, J Hu Current Opinion in Chemical Biology 47, 18-23, 2018 | 15 | 2018 |
The LarB carboxylase/hydrolase forms a transient cysteinyl-pyridine intermediate during nickel-pincer nucleotide cofactor biosynthesis JA Rankin, S Chatterjee, Z Tariq, S Lagishetty, B Desguin, J Hu, ... Proceedings of the National Academy of Sciences 118 (39), e2106202118, 2021 | 11 | 2021 |
Lactate racemase and its niacin-derived, covalently-tethered, nickel cofactor B Desguin, P Soumillion, P Hols, J Hu, RP Hausinger | 4 | 2017 |
Structural and mutational characterization of a malate racemase from the LarA superfamily S Gatreddi, J Urdiain-Arraiza, B Desguin, RP Hausinger, J Hu Biometals 36 (2), 303-313, 2023 | 3 | 2023 |
Versatile capillary electrophoresis method for the direct chiral separation of aliphatic and aromatic α-hydroxy acids, β-hydroxy acids and polyhydroxy acids using vancomycin as … J Urdiain-Arraiza, B Desguin Journal of Chromatography A 1715, 464611, 2024 | 1 | 2024 |
Lactate Racemization and Beyond B Desguin J Bacteriol Parasitol 9 (335), 2, 2018 | 1 | 2018 |
PBP-A, a cyanobacterial DD-peptidase with high specificity for amidated muropeptides, exhibits pH-dependent promiscuous activity harmful to Escherichia coli GM Dorrazehi, M Winkle, M Desmet, V Stroobant, G Tanriver, H Degand, ... | | 2024 |
PBP-A, a cyanobacterial DD-peptidase with high specificity for amidated muropeptides, imposes a pH-dependent fitness cost in Escherichia coli as a consequence of promiscuous … GM Dorrazehi, M Winkle, V Stroobant, H Degand, D Evrard, B Desguin, ... | | 2023 |
Biosynthesis and functions of the Nickel-pincer nucleotide (NPN) B Desguin Novel Enzymes 2023, 2023 | | 2023 |