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Kay Hänggi
Kay Hänggi
Moffitt Cancer Center & Research Institute – Department of Immunology
Verified email at moffitt.org
Title
Cited by
Cited by
Year
The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake
Á de Mingo Pulido, K Hänggi, DP Celias, A Gardner, J Li, ...
Immunity 54 (6), 1154-1167. e7, 2021
1212021
The unfolded protein response mediator PERK governs myeloid cell-driven immunosuppression in tumors through inhibition of STING signaling
E Mohamed, RA Sierra, J Trillo-Tinoco, Y Cao, P Innamarato, KK Payne, ...
Immunity 52 (4), 668-682. e7, 2020
1212020
Targeting p38 or MK2 enhances the anti-leukemic activity of Smac-mimetics
N Lalaoui, K Hänggi, G Brumatti, D Chau, NYN Nguyen, L Vasilikos, ...
Cancer cell 29 (2), 145-158, 2016
1212016
Necroptosis execution is mediated by plasma membrane nanopores independent of calcium
U Ros, A Peña-Blanco, K Hänggi, U Kunzendorf, S Krautwald, ...
Cell reports 19 (1), 175-187, 2017
1202017
Prolyl isomerase PIN1 regulates DNA double-strand break repair by counteracting DNA end resection
M Steger, O Murina, D Hühn, LP Ferretti, R Walser, K Hänggi, L Lafranchi, ...
Molecular cell 50 (3), 333-343, 2013
1002013
FANCD2 and CtIP cooperate to repair DNA interstrand crosslinks
O Murina, C von Aesch, U Karakus, LP Ferretti, HA Bolck, K Hänggi, ...
Cell reports 7 (4), 1030-1038, 2014
912014
The immune microenvironment and cancer metastasis
A El-Kenawi, K Hänggi, B Ruffell
Cold Spring Harbor Perspectives in Medicine 10 (4), a037424, 2020
822020
RIPK1/RIPK3 promotes vascular permeability to allow tumor cell extravasation independent of its necroptotic function
K Hänggi, L Vasilikos, AF Valls, R Yerbes, J Knop, LM Spilgies, K Rieck, ...
Cell death & disease 8 (2), e2588-e2588, 2017
792017
Ovarian cancer immunogenicity is governed by a narrow subset of progenitor tissue-resident memory T cells
CM Anadon, X Yu, K Hänggi, S Biswas, RA Chaurio, A Martin, KK Payne, ...
Cancer Cell 40 (5), 545-557. e13, 2022
662022
Inhibitor of apoptosis protein-1 regulates tumor necrosis factor–mediated destruction of intestinal epithelial cells
T Grabinger, KJ Bode, J Demgenski, C Seitz, ME Delgado, F Kostadinova, ...
Gastroenterology 152 (4), 867-879, 2017
662017
Cell death, therapeutics, and the immune response in cancer
K Hänggi, B Ruffell
Trends in cancer 9 (5), 381-396, 2023
322023
TIM-3 blockade enhances IL-12-dependent antitumor immunity by promoting CD8+ T cell and XCR1+ dendritic cell spatial co-localization
A Gardner, Á de Mingo Pulido, K Hänggi, S Bazargan, A Onimus, ...
Journal for immunotherapy of cancer 10 (1), 2022
252022
Oncogenic KRAS drives immune suppression in colorectal cancer
K Hänggi, B Ruffell
Cancer Cell 35 (4), 535-537, 2019
222019
Targeting intracellular oncoproteins with dimeric IgA promotes expulsion from the cytoplasm and immune-mediated control of epithelial cancers
S Biswas, G Mandal, CM Anadon, RA Chaurio, LU Lopez-Bailon, ...
Immunity 56 (11), 2570-2583. e6, 2023
72023
Loss of cIAP1 in endothelial cells limits metastatic extravasation through tumor-derived lymphotoxin alpha
L Vasilikos, K Hänggi, LM Spilgies, S Kisele, S Rufli, WWL Wong
Cancers 13 (4), 599, 2021
32021
RNAi Screening Uncovers a Synthetic Sick Interaction between CtIP and the BARD1 Tumor Suppressor
HA Bolck, S Przetocka, R Meier, C von Aesch, C Zurfluh, K Hänggi, ...
Cells 11 (4), 643, 2022
22022
Grading of lung adenocarcinomas with simultaneous segmentation by artificial intelligence (GLASS-AI)
JH Lockhart, HD Ackerman, K Lee, M Abdalah, AJ Davis, N Hackel, ...
NPJ Precision Oncology 7 (1), 68, 2023
12023
Abstract PO-082: Automated tumor segmentation, grading, and analysis of tumor heterogeneity in preclinical models of lung adenocarcinoma
JH Lockhart, HD Ackerman, K Lee, M Abdalah, A Davis, N Montey, ...
Clinical Cancer Research 27 (5_Supplement), PO-082-PO-082, 2021
12021
Investigating the mechanisms involved in HMGB1-dependent DNA uptake and STING activation in dendritic cells
DP Celias, K Hänggi, B Ruffell
Cancer Research 83 (7_Supplement), 678-678, 2023
2023
Necroptosis promotes tumor growth through IL1-alpha release and recruitment of immunosuppressive myeloid cells
K Hänggi, A Keske, A Gardner, J Li, O Osunmakinde, D Celias, A Beg, ...
Cancer Research 83 (7_Supplement), 655-655, 2023
2023
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