| Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease C Cruchaga, CM Karch, SC Jin, BA Benitez, Y Cai, R Guerreiro, O Harari, ... Nature 505 (7484), 550-554, 2014 | 523 | 2014 |
| GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer’s disease C Cruchaga, JSK Kauwe, O Harari, SC Jin, Y Cai, CM Karch, BA Benitez, ... Neuron 78 (2), 256-268, 2013 | 379 | 2013 |
| A common haplotype lowers PU. 1 expression in myeloid cells and delays onset of Alzheimer's disease K Huang, E Marcora, AA Pimenova, AF Di Narzo, M Kapoor, SC Jin, ... Nature neuroscience 20 (8), 1052-1061, 2017 | 342 | 2017 |
| Coding variants in TREM2 increase risk for Alzheimer's disease SC Jin, BA Benitez, CM Karch, B Cooper, T Skorupa, D Carrell, JB Norton, ... Human molecular genetics 23 (21), 5838-5846, 2014 | 293 | 2014 |
| An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations U Dube, JL Del-Aguila, Z Li, JP Budde, S Jiang, S Hsu, L Ibanez, ... Nature neuroscience 22 (11), 1903-1912, 2019 | 260 | 2019 |
| TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis F Cignarella, F Filipello, B Bollman, C Cantoni, A Locca, R Mikesell, ... Acta neuropathologica 140, 513-534, 2020 | 224 | 2020 |
| The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer’s disease risk Y Deming, F Filipello, F Cignarella, C Cantoni, S Hsu, R Mikesell, Z Li, ... Science translational medicine 11 (505), eaau2291, 2019 | 206 | 2019 |
| Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy S Da Mesquita, Z Papadopoulos, T Dykstra, L Brase, FG Farias, M Wall, ... Nature 593 (7858), 255-260, 2021 | 200 | 2021 |
| Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers Y Deming, Z Li, M Kapoor, O Harari, JL Del-Aguila, K Black, D Carrell, ... Acta neuropathologica 133 (5), 839-856, 2017 | 200 | 2017 |
| A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain JL Del-Aguila, Z Li, U Dube, KA Mihindukulasuriya, JP Budde, ... Alzheimer's research & therapy 11, 1-16, 2019 | 154 | 2019 |
| Missense variant in TREML2 protects against Alzheimer's disease BA Benitez, SC Jin, R Guerreiro, R Graham, J Lord, D Harold, R Sims, ... Neurobiology of aging 35 (6), 1510. e19-1510. e26, 2014 | 143 | 2014 |
| Genome-wide association study of CSF levels of 59 Alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation JSK Kauwe, MH Bailey, PG Ridge, R Perry, ME Wadsworth, KL Hoyt, ... PLoS genetics 10 (10), e1004758, 2014 | 133 | 2014 |
| Polygenic risk score of sporadic late-onset Alzheimer's disease reveals a shared architecture with the familial and early-onset forms C Cruchaga, JL Del-Aguila, B Saef, K Black, MV Fernandez, J Budde, ... Alzheimer's & Dementia 14 (2), 205-214, 2018 | 128 | 2018 |
| Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders C Yang, FHG Farias, L Ibanez, A Suhy, B Sadler, MV Fernandez, F Wang, ... Nature neuroscience 24 (9), 1302-1312, 2021 | 119 | 2021 |
| Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid A Drieu, S Du, SE Storck, J Rustenhoven, Z Papadopoulos, T Dykstra, ... Nature 611 (7936), 585-593, 2022 | 93 | 2022 |
| A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53 JC Wang, T Foroud, AL Hinrichs, NXH Le, S Bertelsen, JP Budde, ... Molecular psychiatry 18 (11), 1218-1224, 2013 | 91 | 2013 |
| A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks M Kapoor, JC Wang, L Wetherill, N Le, S Bertelsen, AL Hinrichs, J Budde, ... Human genetics 132, 1141-1151, 2013 | 84 | 2013 |
| Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer’s disease resilience PG Ridge, CM Karch, S Hsu, I Arano, CC Teerlink, MTW Ebbert, ... Genome medicine 9, 1-14, 2017 | 83 | 2017 |
| Analysis of whole genome-transcriptomic organization in brain to identify genes associated with alcoholism M Kapoor, JC Wang, SP Farris, Y Liu, J McClintick, I Gupta, JL Meyers, ... Translational psychiatry 9 (1), 89, 2019 | 79 | 2019 |
| Phosphorylated tau-Aβ42 ratio as a continuous trait for biomarker discovery for early-stage Alzheimer’s disease in multiplex immunoassay panels of cerebrospinal fluid O Harari, C Cruchaga, JSK Kauwe, BJ Ainscough, K Bales, EH Pickering, ... Biological psychiatry 75 (9), 723-731, 2014 | 79 | 2014 |
Carlos CruchagaProfessor. NeuroGenomics and Informatics Center DirectorDirección de correo verificada de wustl.edu
