| Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation P Xu, DM Duong, NT Seyfried, D Cheng, Y Xie, J Robert, J Rush, ... Cell 137 (1), 133-145, 2009 | 1386 | 2009 |
| Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation ECB Johnson, EB Dammer, DM Duong, L Ping, M Zhou, L Yin, ... Nature medicine 26 (5), 769-780, 2020 | 632 | 2020 |
| Relative and absolute quantification of postsynaptic density proteome isolated from rat forebrain and cerebellum* S D Cheng, CC Hoogenraad, J Rush, E Ramm, MA Schlager, DM Duong, ... Molecular & cellular proteomics 5 (6), 1158-1170, 2006 | 563 | 2006 |
| Semiquantitative proteomic analysis of rat forebrain postsynaptic density fractions by mass spectrometry J Peng, MJ Kim, D Cheng, DM Duong, SP Gygi, M Sheng Journal of Biological Chemistry 279 (20), 21003-21011, 2004 | 537 | 2004 |
| TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD CC Chou, YI Zhang, ME Umoh, SW Vaughan, I Lorenzini, F Liu, ... Nature neuroscience 21 (2), 228-239, 2018 | 488 | 2018 |
| Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease Z Zhang, M Song, X Liu, SS Kang, IS Kwon, DM Duong, NT Seyfried, ... Nature medicine 20 (11), 1254-1262, 2014 | 407 | 2014 |
| A multi-network approach identifies protein-specific co-expression in asymptomatic and symptomatic Alzheimer’s disease NT Seyfried, EB Dammer, V Swarup, D Nandakumar, DM Duong, L Yin, ... Cell systems 4 (1), 60-72. e4, 2017 | 392 | 2017 |
| Proteomic characterization of postmortem amyloid plaques isolated by laser capture microdissection L Liao, D Cheng, J Wang, DM Duong, TG Losik, M Gearing, HD Rees, ... Journal of Biological Chemistry 279 (35), 37061-37068, 2004 | 351 | 2004 |
| Posttranslational modifications mediate the structural diversity of tauopathy strains T Arakhamia, CE Lee, Y Carlomagno, M Kumar, DM Duong, H Wesseling, ... Cell 180 (4), 633-644. e12, 2020 | 331 | 2020 |
| Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth L Jin, D Li, GN Alesi, J Fan, HB Kang, Z Lu, TJ Boggon, P Jin, H Yi, ... Cancer cell 27 (2), 257-270, 2015 | 323 | 2015 |
| The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease M Wang, ND Beckmann, P Roussos, E Wang, X Zhou, Q Wang, C Ming, ... Scientific data 5 (1), 1-16, 2018 | 310 | 2018 |
| Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer’s disease S Rangaraju, EB Dammer, SA Raza, P Rathakrishnan, H Xiao, T Gao, ... Molecular neurodegeneration 13, 1-25, 2018 | 305 | 2018 |
| U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer’s disease B Bai, CM Hales, PC Chen, Y Gozal, EB Dammer, JJ Fritz, X Wang, Q Xia, ... Proceedings of the National Academy of Sciences 110 (41), 16562-16567, 2013 | 302 | 2013 |
| Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer’s disease Z Zhang, M Song, X Liu, S Su Kang, DM Duong, NT Seyfried, X Cao, ... Nature communications 6 (1), 8762, 2015 | 262 | 2015 |
| Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level ECB Johnson, EK Carter, EB Dammer, DM Duong, ES Gerasimov, Y Liu, ... Nature neuroscience 25 (2), 213-225, 2022 | 236 | 2022 |
| Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer’s disease L Higginbotham, L Ping, EB Dammer, DM Duong, M Zhou, M Gearing, ... Science advances 6 (43), eaaz9360, 2020 | 213 | 2020 |
| Polyubiquitin linkage profiles in three models of proteolytic stress suggest the etiology of Alzheimer disease EB Dammer, CH Na, P Xu, NT Seyfried, DM Duong, D Cheng, M Gearing, ... Journal of biological chemistry 286 (12), 10457-10465, 2011 | 210 | 2011 |
| Proteomic identification of novel proteins associated with Lewy bodies Q Xia, L Liao, D Cheng, DM Duong, M Gearing, JJ Lah, AI Levey, J Peng Frontiers in bioscience: a journal and virtual library 13, 3850, 2008 | 193 | 2008 |
| Systematical optimization of reverse-phase chromatography for shotgun proteomics P Xu, DM Duong, J Peng Journal of proteome research 8 (8), 3944-3950, 2009 | 189 | 2009 |
| Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer’s disease pathogenesis AP Wingo, Y Liu, ES Gerasimov, J Gockley, BA Logsdon, DM Duong, ... Nature genetics 53 (2), 143-146, 2021 | 182 | 2021 |
Nicholas SeyfriedProfessor of Biochemistry, Emory School of MedicineDirección de correo verificada de emory.edu
