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Raveen Rathnasinghe
Raveen Rathnasinghe
Investigator/Manager Molecular virology - CSL Seqirus
Verified email at seqirus.com - Homepage
Title
Cited by
Cited by
Year
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing
L Riva, S Yuan, X Yin, L Martin-Sancho, N Matsunaga, L Pache, ...
Nature 586 (7827), 113-119, 2020
7272020
SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling
L Miorin, T Kehrer, MT Sanchez-Aparicio, K Zhang, P Cohen, RS Patel, ...
Proceedings of the National Academy of Sciences 117 (45), 28344-28354, 2020
4732020
SARS-CoV-2 spike E484K mutation reduces antibody neutralisation
S Jangra, C Ye, R Rathnasinghe, D Stadlbauer, H Alshammary, ...
The Lancet Microbe 2 (7), e283-e284, 2021
3972021
Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A
KM White, R Rosales, S Yildiz, T Kehrer, L Miorin, E Moreno, S Jangra, ...
Science 371 (6532), 926-931, 2021
2972021
Comparison of transgenic and adenovirus hACE2 mouse models for SARS-CoV-2 infection
R Rathnasinghe, S Strohmeier, F Amanat, VL Gillespie, F Krammer, ...
Emerging microbes & infections 9 (1), 2433-2445, 2020
1732020
Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2
TA Tummino, VV Rezelj, B Fischer, A Fischer, MJ O’meara, B Monel, ...
Science 373 (6554), 541-547, 2021
1622021
Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission
A Escalera, AS Gonzalez-Reiche, S Aslam, I Mena, M Laporte, RL Pearl, ...
Cell host & microbe 30 (3), 373-387. e7, 2022
1452022
The E484K mutation in the SARS-CoV-2 spike protein reduces but does not abolish neutralizing activity of human convalescent and post-vaccination sera.
S Jangra, C Ye, R Rathnasinghe, D Stadlbauer, F Krammer, V Simon, ...
MedRxiv, 2021
1372021
The N501Y mutation in SARS-CoV-2 spike leads to morbidity in obese and aged mice and is neutralized by convalescent and post-vaccination human sera
R Rathnasinghe, S Jangra, A Cupic, C Martínez-Romero, LCF Mulder, ...
MedRxiv, 2021
1132021
Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection
D Kaul, R Rathnasinghe, M Ferres, GS Tan, A Barrera, BE Pickett, ...
Nature communications 11 (1), 2537, 2020
932020
TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation
JSY Ho, BWY Mok, L Campisi, T Jordan, S Yildiz, S Parameswaran, ...
Cell 184 (10), 2618-2632. e17, 2021
832021
A Newcastle disease virus expressing a stabilized spike protein of SARS-CoV-2 induces protective immune responses
W Sun, Y Liu, F Amanat, I González-Domínguez, S McCroskery, ...
Nature communications 12 (1), 6197, 2021
612021
Sterilizing immunity against SARS‐CoV‐2 infection in mice by a single‐shot and lipid amphiphile imidazoquinoline TLR7/8 agonist‐adjuvanted recombinant spike protein vaccine
S Jangra, J De Vrieze, A Choi, R Rathnasinghe, G Laghlali, A Uvyn, ...
Angewandte Chemie International Edition 60 (17), 9467-9473, 2021
502021
Limited extent and consequences of pancreatic SARS-CoV-2 infection
V van der Heide, S Jangra, P Cohen, R Rathnasinghe, S Aslam, T Aydillo, ...
Cell Reports 38 (11), 2022
492022
Introduction of two prolines and removal of the polybasic cleavage site lead to higher efficacy of a recombinant spike-based SARS-CoV-2 vaccine in the mouse model
F Amanat, S Strohmeier, R Rathnasinghe, M Schotsaert, L Coughlan, ...
MBio 12 (2), 10.1128/mbio. 02648-20, 2021
462021
COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models
P Maisonnasse, Y Aldon, A Marc, R Marlin, N Dereuddre-Bosquet, ...
Nature communications 12 (1), 6097, 2021
432021
SARS-CoV-2 spike E484K mutation reduces antibody neutralisation. Lancet Microbe 2: e283–e284
S Jangra, C Ye, R Rathnasinghe, D Stadlbauer, F Krammer, V Simon, ...
402021
The virucidal effects of 405 nm visible light on SARS-CoV-2 and influenza A virus
R Rathnasinghe, S Jangra, L Miorin, M Schotsaert, C Yahnke, ...
Scientific Reports 11 (1), 19470, 2021
382021
Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis
T Kehrer, A Cupic, C Ye, S Yildiz, M Bouhaddou, NA Crossland, ...
Cell Host & Microbe 31 (10), 1668-1684. e12, 2023
272023
Scalable, effective, and rapid decontamination of SARS-CoV-2 contaminated N95 respirators using germicidal ultraviolet C (UVC) irradiation device
R Rathnasinghe, RF Karlicek Jr, M Schotsaert, M Koffas, BL Arduini, ...
Scientific Reports 11 (1), 19970, 2021
262021
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