Chuck Harrell
Chuck Harrell
Virginia Commonwealth University
Dirección de correo verificada de vcuhealth.org
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Lessons in estrogen biology from knockout and transgenic animals
SC Hewitt, JC Harrell, KS Korach
Annu. Rev. Physiol. 67, 285-308, 2005
3242005
The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-β signaling
DS Micalizzi, KL Christensen, P Jedlicka, RD Coletta, AE Barón, ...
The Journal of clinical investigation 119 (9), 2678-2690, 2009
2342009
A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis
E Wagenblast, M Soto, S Gutiérrez-Ángel, CA Hartl, AL Gable, AR Maceli, ...
Nature 520 (7547), 358-362, 2015
2332015
Genomic analysis identifies unique signatures predictive of brain, lung, and liver relapse
JC Harrell, A Prat, JS Parker, C Fan, X He, L Carey, C Anders, M Ewend, ...
Breast cancer research and treatment 132 (2), 523-535, 2012
1972012
Taxonomy of breast cancer based on normal cell phenotype predicts outcome
S Santagata, A Thakkar, A Ergonul, B Wang, T Woo, R Hu, JC Harrell, ...
The Journal of clinical investigation 124 (2), 859-870, 2014
1782014
Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes
A Prat, O Karginova, JS Parker, C Fan, X He, L Bixby, JC Harrell, ...
Breast cancer research and treatment 142 (2), 237-255, 2013
1602013
Asparagine bioavailability governs metastasis in a model of breast cancer
SRV Knott, E Wagenblast, S Khan, SY Kim, M Soto, M Wagner, ...
Nature 554 (7692), 378-381, 2018
1542018
Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenografts
KB Horwitz, WW Dye, JC Harrell, P Kabos, CA Sartorius
Proceedings of the National Academy of Sciences 105 (15), 5774-5779, 2008
1502008
Estrogen receptor positive breast cancer metastasis: altered hormonal sensitivity and tumor aggressiveness in lymphatic vessels and lymph nodes
JC Harrell, WW Dye, DC Allred, P Jedlicka, NS Spoelstra, CA Sartorius, ...
Cancer research 66 (18), 9308-9315, 2006
1472006
Characterization of twenty-five ovarian tumour cell lines that phenocopy primary tumours
TA Ince, AD Sousa, MA Jones, JC Harrell, ES Agoston, M Krohn, ...
Nature communications 6 (1), 1-14, 2015
1312015
Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts
AD Pfefferle, JI Herschkowitz, J Usary, JC Harrell, BT Spike, JR Adams, ...
Genome biology 14 (11), R125, 2013
1302013
SIX1 induces lymphangiogenesis and metastasis via upregulation of VEGF-C in mouse models of breast cancer
CA Wang, P Jedlicka, AN Patrick, DS Micalizzi, KC Lemmer, E Deitsch, ...
The Journal of clinical investigation 122 (5), 1895-1906, 2012
1212012
Patient-derived luminal breast cancer xenografts retain hormone receptor heterogeneity and help define unique estrogen-dependent gene signatures
P Kabos, J Finlay-Schultz, C Li, E Kline, C Finlayson, J Wisell, CA Manuel, ...
Breast cancer research and treatment 135 (2), 415-432, 2012
1092012
Interactions with fibroblasts are distinct in Basal-like and luminal breast cancers
JT Camp, F Elloumi, E Roman-Perez, J Rein, DA Stewart, JC Harrell, ...
Molecular Cancer Research 9 (1), 3-13, 2011
992011
Maintenance of hormone responsiveness in luminal breast cancers by suppression of Notch
JM Haughian, MP Pinto, JC Harrell, BS Bliesner, KM Joensuu, WW Dye, ...
Proceedings of the National Academy of Sciences 109 (8), 2742-2747, 2012
982012
Update on animal models developed for analyses of estrogen receptor biological activity
KS Korach, JMA Emmen, VR Walker, SC Hewitt, M Yates, JM Hall, ...
The Journal of steroid biochemistry and molecular biology 86 (3-5), 387-391, 2003
972003
Spontaneous fusion with, and transformation of mouse stroma by, malignant human breast cancer epithelium
BM Jacobsen, JC Harrell, P Jedlicka, VF Borges, M Varella-Garcia, ...
Cancer research 66 (16), 8274-8279, 2006
892006
Expression of Six1 in luminal breast cancers predicts poor prognosis and promotes increases in tumor initiating cells by activation of extracellular signal-regulated kinase and …
R Iwanaga, CA Wang, DS Micalizzi, JC Harrell, P Jedlicka, CA Sartorius, ...
Breast Cancer Research 14 (4), R100, 2012
872012
Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases
B Adamo, AM Deal, E Burrows, J Geradts, E Hamilton, KL Blackwell, ...
Breast Cancer Research 13 (6), R125, 2011
772011
Tissue-specific pathways for estrogen regulation of ovarian cancer growth and metastasis
MA Spillman, NG Manning, WW Dye, CA Sartorius, MD Post, JC Harrell, ...
Cancer research 70 (21), 8927-8936, 2010
692010
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
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