|Lessons in estrogen biology from knockout and transgenic animals|
SC Hewitt, JC Harrell, KS Korach
Annu. Rev. Physiol. 67, 285-308, 2005
|The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-β signaling|
DS Micalizzi, KL Christensen, P Jedlicka, RD Coletta, AE Barón, ...
The Journal of clinical investigation 119 (9), 2678-2690, 2009
|A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis|
E Wagenblast, M Soto, S Gutiérrez-Ángel, CA Hartl, AL Gable, AR Maceli, ...
Nature 520 (7547), 358-362, 2015
|Genomic analysis identifies unique signatures predictive of brain, lung, and liver relapse|
JC Harrell, A Prat, JS Parker, C Fan, X He, L Carey, C Anders, M Ewend, ...
Breast cancer research and treatment 132 (2), 523-535, 2012
|Taxonomy of breast cancer based on normal cell phenotype predicts outcome|
S Santagata, A Thakkar, A Ergonul, B Wang, T Woo, R Hu, JC Harrell, ...
The Journal of clinical investigation 124 (2), 859-870, 2014
|Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes|
A Prat, O Karginova, JS Parker, C Fan, X He, L Bixby, JC Harrell, ...
Breast cancer research and treatment 142 (2), 237-255, 2013
|Asparagine bioavailability governs metastasis in a model of breast cancer|
SRV Knott, E Wagenblast, S Khan, SY Kim, M Soto, M Wagner, ...
Nature 554 (7692), 378-381, 2018
|Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenografts|
KB Horwitz, WW Dye, JC Harrell, P Kabos, CA Sartorius
Proceedings of the National Academy of Sciences 105 (15), 5774-5779, 2008
|Estrogen receptor positive breast cancer metastasis: altered hormonal sensitivity and tumor aggressiveness in lymphatic vessels and lymph nodes|
JC Harrell, WW Dye, DC Allred, P Jedlicka, NS Spoelstra, CA Sartorius, ...
Cancer research 66 (18), 9308-9315, 2006
|Characterization of twenty-five ovarian tumour cell lines that phenocopy primary tumours|
TA Ince, AD Sousa, MA Jones, JC Harrell, ES Agoston, M Krohn, ...
Nature communications 6 (1), 1-14, 2015
|Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts|
AD Pfefferle, JI Herschkowitz, J Usary, JC Harrell, BT Spike, JR Adams, ...
Genome biology 14 (11), R125, 2013
|SIX1 induces lymphangiogenesis and metastasis via upregulation of VEGF-C in mouse models of breast cancer|
CA Wang, P Jedlicka, AN Patrick, DS Micalizzi, KC Lemmer, E Deitsch, ...
The Journal of clinical investigation 122 (5), 1895-1906, 2012
|Patient-derived luminal breast cancer xenografts retain hormone receptor heterogeneity and help define unique estrogen-dependent gene signatures|
P Kabos, J Finlay-Schultz, C Li, E Kline, C Finlayson, J Wisell, CA Manuel, ...
Breast cancer research and treatment 135 (2), 415-432, 2012
|Interactions with fibroblasts are distinct in Basal-like and luminal breast cancers|
JT Camp, F Elloumi, E Roman-Perez, J Rein, DA Stewart, JC Harrell, ...
Molecular Cancer Research 9 (1), 3-13, 2011
|Maintenance of hormone responsiveness in luminal breast cancers by suppression of Notch|
JM Haughian, MP Pinto, JC Harrell, BS Bliesner, KM Joensuu, WW Dye, ...
Proceedings of the National Academy of Sciences 109 (8), 2742-2747, 2012
|Update on animal models developed for analyses of estrogen receptor biological activity|
KS Korach, JMA Emmen, VR Walker, SC Hewitt, M Yates, JM Hall, ...
The Journal of steroid biochemistry and molecular biology 86 (3-5), 387-391, 2003
|Spontaneous fusion with, and transformation of mouse stroma by, malignant human breast cancer epithelium|
BM Jacobsen, JC Harrell, P Jedlicka, VF Borges, M Varella-Garcia, ...
Cancer research 66 (16), 8274-8279, 2006
|Expression of Six1 in luminal breast cancers predicts poor prognosis and promotes increases in tumor initiating cells by activation of extracellular signal-regulated kinase and …|
R Iwanaga, CA Wang, DS Micalizzi, JC Harrell, P Jedlicka, CA Sartorius, ...
Breast Cancer Research 14 (4), R100, 2012
|Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases|
B Adamo, AM Deal, E Burrows, J Geradts, E Hamilton, KL Blackwell, ...
Breast Cancer Research 13 (6), R125, 2011
|Tissue-specific pathways for estrogen regulation of ovarian cancer growth and metastasis|
MA Spillman, NG Manning, WW Dye, CA Sartorius, MD Post, JC Harrell, ...
Cancer research 70 (21), 8927-8936, 2010