Diego L. Medina
Diego L. Medina
Head, High Content Screening Facility, Telethon Institute of Genetics and Medicine (TIGEM)
Verified email at
Cited by
Cited by
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
TFEB links autophagy to lysosomal biogenesis
C Settembre, C Di Malta, VA Polito, MG Arencibia, F Vetrini, S Erdin, ...
science 332 (6036), 1429-1433, 2011
A gene network regulating lysosomal biogenesis and function
M Sardiello, M Palmieri, A Di Ronza, DL Medina, M Valenza, ...
Science 325 (5939), 473-477, 2009
A lysosome‐to‐nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
C Settembre, R Zoncu, DL Medina, F Vetrini, S Erdin, SU Erdin, T Huynh, ...
The EMBO journal 31 (5), 1095-1108, 2012
Signals from the lysosome: a control centre for cellular clearance and energy metabolism
C Settembre, A Fraldi, DL Medina, A Ballabio
Nature reviews Molecular cell biology 14 (5), 283-296, 2013
Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB
DL Medina, S Di Paola, I Peluso, A Armani, D De Stefani, R Venditti, ...
Nature cell biology 17 (3), 288-299, 2015
Transcriptional activation of lysosomal exocytosis promotes cellular clearance
DL Medina, A Fraldi, V Bouche, F Annunziata, G Mansueto, ...
Developmental cell 21 (3), 421-430, 2011
Mechanism of TrkB-mediated hippocampal long-term potentiation
L Minichiello, AM Calella, DL Medina, T Bonhoeffer, R Klein, M Korte
Neuron 36 (1), 121-137, 2002
A block of autophagy in lysosomal storage disorders
C Settembre, A Fraldi, L Jahreiss, C Spampanato, C Venturi, D Medina, ...
Human molecular genetics 17 (1), 119-129, 2008
Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition
A Luciani, VR Villella, S Esposito, N Brunetti-Pierri, D Medina, ...
Nature cell biology 12 (9), 863-875, 2010
mTOR-dependent phosphorylation controls TFEB nuclear export
G Napolitano, A Esposito, H Choi, M Matarese, V Benedetti, C Di Malta, ...
Nature communications 9 (1), 3312, 2018
Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders
A Fraldi, F Annunziata, A Lombardi, HJ Kaiser, DL Medina, ...
The EMBO journal 29 (21), 3607-3620, 2010
FGF signalling regulates bone growth through autophagy
L Cinque, A Forrester, R Bartolomeo, M Svelto, R Venditti, S Montefusco, ...
Nature 528 (7581), 272-275, 2015
A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition
JX Song, YR Sun, I Peluso, Y Zeng, X Yu, JH Lu, Z Xu, MZ Wang, LF Liu, ...
Autophagy 12 (8), 1372-1389, 2016
Clinical challenges and future therapeutic approaches for neuronal ceroid lipofuscinosis
SE Mole, G Anderson, HA Band, SF Berkovic, JD Cooper, SMK Holthaus, ...
The Lancet Neurology 18 (1), 107-116, 2019
Autophagosome–lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL
MG De Leo, L Staiano, M Vicinanza, A Luciani, A Carissimo, M Mutarelli, ...
Nature cell biology 18 (8), 839-850, 2016
Brain disorders due to lysosomal dysfunction
A Fraldi, AD Klein, DL Medina, C Settembre
Annual review of neuroscience 39 (1), 277-295, 2016
The rapidly evolving view of lysosomal storage diseases
G Parenti, DL Medina, A Ballabio
EMBO molecular medicine 13 (2), e12836, 2021
TRPML1: The Ca (2+) retaker of the lysosome
S Di Paola, A Scotto-Rosato, DL Medina
Cell calcium 69, 112-121, 2018
TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKKβ/VPS34 pathway
A Scotto Rosato, S Montefusco, C Soldati, S Di Paola, A Capuozzo, ...
Nature communications 10 (1), 5630, 2019
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