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Florin Despa
Florin Despa
Professor of Pharmacology, University of Kentucky
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Cognitive decline and dementia in diabetes mellitus: mechanisms and clinical implications
GJ Biessels, F Despa
Nature Reviews Endocrinology 14 (10), 591-604, 2018
9392018
Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation
JR Erickson, L Pereira, L Wang, G Han, A Ferguson, K Dao, RJ Copeland, ...
Nature 502 (7471), 372-376, 2013
6262013
Amylin deposition in the brain: a second amyloid in Alzheimer disease?
K Jackson, GA Barisone, E Diaz, L Jin, C DeCarli, F Despa
Annals of neurology 74 (4), 517-526, 2013
3642013
Production of bimetallic clusters by a dual-target dual-laser vaporization source
W Bouwen, P Thoen, F Vanhoutte, S Bouckaert, F Despa, H Weidele, ...
Review of Scientific Instruments 71 (1), 54-58, 2000
2002000
Stability effects of AunXm+ (X= Cu, Al, Y, In) clusters
W Bouwen, F Vanhoutte, F Despa, S Bouckaert, S Neukermans, LT Kuhn, ...
Chemical physics letters 314 (3-4), 227-233, 1999
1721999
The relative thermal stability of tissue macromolecules and cellular structure in burn injury
F Despa, DP Orgill, J Neuwalder, RC Lee
burns 31 (5), 568-577, 2005
1682005
Neuroinflammation and neurologic deficits in diabetes linked to brain accumulation of amylin
S Srodulski, S Sharma, AB Bachstetter, JM Brelsfoard, C Pascual, XS Xie, ...
Molecular neurodegeneration 9, 1-12, 2014
1542014
Dielectric modulation of biological water
F Despa, A Fernández, RS Berry
Physical Review Letters 93 (22), 228104, 2004
1482004
Hyperamylinemia contributes to cardiac dysfunction in obesity and diabetes: a study in humans and rats
S Despa, KB Margulies, LE Chen, AA Knowlton, PJ Havel, H Taegtmeyer, ...
Circulation research 110 (4), 598-608, 2012
1422012
Intracellular Na+ Concentration ([Na+]i) Is Elevated in Diabetic Hearts Due to Enhanced Na+–Glucose Cotransport
R Lambert, S Srodulski, X Peng, KB Margulies, F Despa, S Despa
Journal of the American Heart Association 4 (9), e002183, 2015
1222015
The origin of long-range attraction between hydrophobes in water
F Despa, RS Berry
Biophysical Journal 92 (2), 373-378, 2007
832007
Sodium-myoinositol cotransporter-1, SMIT1, mediates the production of reactive oxygen species induced by hyperglycemia in the heart
A Van Steenbergen, M Balteau, A Ginion, L Ferté, S Battault, ...
Scientific reports 7 (1), 41166, 2017
782017
Intraneuronal amylin deposition, peroxidative membrane injury and increased IL-1β synthesis in brains of Alzheimer’s disease patients with type-2 diabetes and in diabetic HIP rats
N Verma, H Ly, M Liu, J Chen, H Zhu, M Chow, LB Hersh, F Despa
Journal of Alzheimer's Disease 53 (1), 259-272, 2016
762016
Brain microvascular injury and white matter disease provoked by diabetes‐associated hyperamylinemia
H Ly, N Verma, F Wu, M Liu, KE Saatman, PT Nelson, JT Slevin, ...
Annals of neurology 82 (2), 208-222, 2017
752017
Structural and functional recovery of electropermeabilized skeletal muscle in-vivo after treatment with surfactant poloxamer 188
JM Collins, F Despa, RC Lee
Biochimica et Biophysica Acta (BBA)-Biomembranes 1768 (5), 1238-1246, 2007
742007
Molecular crowding effects on protein stability
F Despa, DP Orgill, RC Lee
Annals of the New York Academy of Sciences 1066 (1), 54-66, 2006
742006
Biological water: Its vital role in macromolecular structure and function
F Despa
Annals of the New York Academy of Sciences 1066 (1), 1-11, 2006
602006
Cardioprotection by controlling hyperamylinemia in a “humanized” diabetic rat model
S Despa, S Sharma, TR Harris, H Dong, N Li, N Chiamvimonvat, ...
Journal of the American Heart Association 3 (4), e001015, 2014
502014
Amylin: what might be its role in Alzheimer’s disease and how could this affect therapy?
F Despa, C DeCarli
Expert review of proteomics 10 (5), 403-405, 2013
392013
Diabetic microcirculatory disturbances and pathologic erythropoiesis are provoked by deposition of amyloid-forming amylin in red blood cells and capillaries
N Verma, M Liu, H Ly, A Loria, KS Campbell, H Bush, PA Kern, PA Jose, ...
Kidney international 97 (1), 143-155, 2020
382020
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