| Asymmetric aldol reaction using immobilized proline on mesoporous support F Calderón, R Fernández, F Sánchez, A Fernández‐Mayoralas Advanced Synthesis & Catalysis 347 (10), 1395-1403, 2005 | 157 | 2005 |
| Asymmetric aldol reaction catalyzed by a heterogenized proline on a mesoporous support. The role of the nature of solvents EG Doyagüez, F Calderon, F Sanchez, A Fernandez-Mayoralas The Journal of Organic Chemistry 72 (24), 9353-9356, 2007 | 133 | 2007 |
| A high throughput screen for next-generation leads targeting malaria parasite transmission MJ Delves, C Miguel-Blanco, H Matthews, I Molina, A Ruecker, S Yahiya, ... Nature communications 9 (1), 3805, 2018 | 113 | 2018 |
| An invitation to open innovation in malaria drug discovery: 47 quality starting points from the TCAMS F Calderón, D Barros, JM Bueno, JM Coterón, E Fernández, FJ Gamo, ... ACS Medicinal Chemistry Letters 2 (10), 741-746, 2011 | 93 | 2011 |
| Open source drug discovery: highly potent antimalarial compounds derived from the tres cantos arylpyrroles AE Williamson, PM Ylioja, MN Robertson, Y Antonova-Koch, V Avery, ... ACS central science 2 (10), 687-701, 2016 | 87 | 2016 |
| Antimalarial chemotherapy: natural product inspired development of preclinical and clinical candidates with diverse mechanisms of action: miniperspective E Fernandez-Alvaro, WD Hong, GL Nixon, PM O’Neill, F Calderon Journal of medicinal chemistry 59 (12), 5587-5603, 2016 | 75 | 2016 |
| Synthesis of azasugars through a proline-catalyzed reaction F Calderón, EG Doyagüez, A Fernández-Mayoralas The Journal of Organic Chemistry 71 (16), 6258-6261, 2006 | 74 | 2006 |
| CODES, a novel procedure for ligand-based virtual screening: PDE7 inhibitors as an application example A Castro, MJ Jerez, C Gil, F Calderón, T Doménech, A Nueda, A Martínez European journal of medicinal chemistry 43 (7), 1349-1359, 2008 | 59 | 2008 |
| Origins of the double asymmetric induction on proline-catalyzed aldol reactions. F Calderon, EG Doyagueez, PH Cheong, A Fernandez-Mayoralas, ... The Journal of Organic Chemistry 73 (20), 7916-7920, 2008 | 51 | 2008 |
| Antimalarial drug discovery: recent progress and future directions F Calderón, DM Wilson, FJ Gamo Progress in medicinal chemistry 52, 97-151, 2013 | 46 | 2013 |
| A new in vivo screening paradigm to accelerate antimalarial drug discovery MB Jiménez-Díaz, S Viera, J Ibanez, T Mulet, N Magan-Marchal, H Garuti, ... PloS one 8 (6), e66967, 2013 | 43 | 2013 |
| Development of Chemical Entities Endowed with Potent Fast-Killing Properties against Plasmodium falciparum Malaria Parasites AN Matralis, A Malik, M Penzo, I Moreno, MJ Almela, I Camino, B Crespo, ... Journal of medicinal chemistry 62 (20), 9217-9235, 2019 | 34 | 2019 |
| Relative and Absolute Stereochemistry of Secondary/Secondary Diols: Low-Temperature 1H NMR of Their bis-MPA Esters F Freire, F Calderón, JM Seco, A Fernández-Mayoralas, E Quinoá, ... The Journal of Organic Chemistry 72 (7), 2297-2301, 2007 | 30 | 2007 |
| Carbamoyl triazoles, known serine protease inhibitors, are a potent new class of antimalarials M McConville, J Fernández, Í Angulo-Barturen, N Bahamontes-Rosa, ... Journal of medicinal chemistry 58 (16), 6448-6455, 2015 | 27 | 2015 |
| Identification of Selective Inhibitors of Plasmodium N-Myristoyltransferase by High-Throughput Screening A Harupa, L De Las Heras, G Colmenarejo, S Lyons-Abbott, A Reers, ... Journal of Medicinal Chemistry 63 (2), 591-600, 2019 | 24 | 2019 |
| A Divergent SAR Study Allows Optimization of a Potent 5-HT2c Inhibitor to a Promising Antimalarial Scaffold F Calderón, J Vidal-Mas, J Burrows, JC de la Rosa, MB Jiménez-Díaz, ... ACS Medicinal Chemistry Letters 3 (5), 373-377, 2012 | 24 | 2012 |
| Synthesis and Structure–Activity Relationships of the Novel Antimalarials 5-Pyridinyl-4(1H)-Pyridones JM Bueno, F Calderon, J Chicharro, JC De la Rosa, B Díaz, J Fernández, ... Journal of Medicinal Chemistry 61 (8), 3422-3435, 2018 | 20 | 2018 |
| Efforts aimed to reduce attrition in antimalarial drug discovery: a systematic evaluation of the current antimalarial targets portfolio MJ Chaparro, F Calderón, P Castañeda, E Fernández-Alvaro, R Gabarró, ... ACS Infectious Diseases 4 (4), 568-576, 2018 | 20 | 2018 |
| A Developability-Focused Optimization Approach Allows Identification of in Vivo Fast-Acting Antimalarials: N-[3-[(Benzimidazol-2-yl)amino]propyl]amides L Keurulainen, M Vahermo, M Puente-Felipe, E Sandoval-Izquierdo, ... Journal of Medicinal Chemistry 58 (11), 4573-4580, 2015 | 17 | 2015 |
| Expanding bromodomain targeting into neglected parasitic diseases C Tallant, P Bamborough, C Chung, FJ Gamo, R Kirkpatrick, C Larminie, ... ACS Infectious Diseases 7 (11), 2953-2958, 2021 | 13 | 2021 |
