| The signaling lipid PI(3,5)P2 stabilizes V1–Vo sector interactions and activates the V-ATPase SC Li, TT Diakov, T Xu, M Tarsio, W Zhu, S Couoh-Cardel, LS Weisman, ... Molecular biology of the cell 25 (8), 1251-1262, 2014 | 149 | 2014 |
| Mechanisms of noncovalent β subunit regulation of NaV channel gating W Zhu, TL Voelker, Z Varga, AR Schubert, JM Nerbonne, JR Silva Journal of General Physiology 149 (8), 813-831, 2017 | 72 | 2017 |
| Predicting patient response to the antiarrhythmic mexiletine based on genetic variation: personalized medicine for long QT syndrome W Zhu, A Mazzanti, TL Voelker, P Hou, JD Moreno, P Angsutararux, ... Circulation research 124 (4), 539-552, 2019 | 57 | 2019 |
| Direct Measurement of Cardiac Na+ Channel Conformations Reveals Molecular Pathologies of Inherited Mutations Z Varga, W Zhu, AR Schubert, JL Pardieck, A Krumholz, EJ Hsu, ... Circulation: Arrhythmia and Electrophysiology 8 (5), 1228-1239, 2015 | 43 | 2015 |
| Mechanisms and models of cardiac sodium channel inactivation KE Mangold, BD Brumback, P Angsutararux, TL Voelker, W Zhu, ... Channels 11 (6), 517-533, 2017 | 37 | 2017 |
| PIEZO1 mediates a mechanothrombotic pathway in diabetes W Zhu, S Guo, M Homilius, C Nsubuga, SH Wright, D Quan, A Kc, ... Science Translational Medicine 14 (626), eabk1707, 2022 | 32 | 2022 |
| Regulation of Na+ channel inactivation by the DIII and DIV voltage-sensing domains EJ Hsu, W Zhu, AR Schubert, T Voelker, Z Varga, JR Silva Journal of General Physiology 149 (3), 389-403, 2017 | 31 | 2017 |
| Molecular motions that shape the cardiac action potential: Insights from voltage clamp fluorometry W Zhu, Z Varga, JR Silva Progress in biophysics and molecular biology 120 (1-3), 3-17, 2016 | 28 | 2016 |
| A novel NaV1. 5 voltage sensor mutation associated with severe atrial and ventricular arrhythmias HG Wang, W Zhu, RJ Kanter, JR Silva, C Honeywell, RM Gow, GS Pitt Journal of molecular and cellular cardiology 92, 52-62, 2016 | 25 | 2016 |
| A Molecularly Detailed NaV1.5 Model Reveals a New Class I Antiarrhythmic Target JD Moreno, W Zhu, K Mangold, W Chung, JR Silva Basic to Translational Science 4 (6), 736-751, 2019 | 20 | 2019 |
| Molecular pathology of sodium channel beta-subunit variants P Angsutararux, W Zhu, TL Voelker, JR Silva Frontiers in Pharmacology 12, 761275, 2021 | 18 | 2021 |
| Conservation and divergence in NaChBac and NaV1.7 pharmacology reveals novel drug interaction mechanisms W Zhu, T Li, JR Silva, J Chen Scientific reports 10 (1), 10730, 2020 | 18 | 2020 |
| Depolarization of the conductance-voltage relationship in the NaV1.5 mutant, E1784K, is due to altered fast inactivation CH Peters, A Yu, W Zhu, JR Silva, PC Ruben PLoS One 12 (9), e0184605, 2017 | 17 | 2017 |
| Gating control of the cardiac sodium channel Nav1. 5 by its β3-subunit involves distinct roles for a transmembrane glutamic acid and the extracellular domain SC Salvage, W Zhu, ZF Habib, SS Hwang, JR Irons, CLH Huang, JR Silva, ... Journal of Biological Chemistry 294 (51), 19752-19763, 2019 | 14 | 2019 |
| Modulation of the effects of class Ib antiarrhythmics on cardiac NaV1. 5-encoded channels by accessory NaVβ subunits W Zhu, W Wang, P Angsutararux, RL Mellor, LL Isom, JM Nerbonne, ... JCI insight 6 (15), 2021 | 10 | 2021 |
| Conformations of voltage-sensing domain III differentially define NaV channel closed- and open-state inactivation P Angsutararux, PW Kang, W Zhu, JR Silva Journal of General Physiology 153 (9), e202112891, 2021 | 10 | 2021 |
| Chinese herbal medicine for the treatment of cardiovascular diseases─ targeting cardiac ion channels Z Yan, L Zhong, W Zhu, SK Chung, P Hou Pharmacological Research, 106765, 2023 | 4 | 2023 |
| Single cell biology: exploring somatic cell behaviors, competition and selection in chronic disease W Zhu, RC Deo, CA MacRae Frontiers in Pharmacology 13, 867431, 2022 | 1 | 2022 |
| A Novel Role for Piezo1 in Diabetes-Associated Thrombosis W Zhu, C Nsubuga, S Wright, M Beerens, T Kiviniemi, V Raskin, RC Deo, ... Biophysical Journal 118 (3), 398a, 2020 | 1 | 2020 |
| A novel low-cost cellular functional assay reveals a potential role for Piezo1 in hyperglycemia induced microcirculatory disorders W Zhu, M Beerens, TO Kiviniemi, E Wilson, RC Deo, CA Macrae Circulation 140 (Suppl_1), A13908-A13908, 2019 | 1 | 2019 |
Jonathan SilvaWashington University in St. LouisVerified email at wustl.edu
