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Joan Fernández Esmerats
Joan Fernández Esmerats
Dirección de correo verificada de gatech.edu
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Disturbed flow increases UBE2C (Ubiquitin E2 Ligase C) via Loss of miR-483-3p, inducing aortic valve calcification by the pVHL (von Hippel-Lindau Protein) and HIF-1α (Hypoxia …
J Fernandez Esmerats, N Villa-Roel, S Kumar, L Gu, MT Salim, M Ohh, ...
Arteriosclerosis, thrombosis, and vascular biology 39 (3), 467-481, 2019
642019
Shear-sensitive genes in aortic valve endothelium
J Fernández Esmerats, J Heath, H Jo
Antioxidants & redox signaling 25 (7), 401-414, 2016
532016
Identification of side-and shear-dependent microRNAs regulating porcine aortic valve pathogenesis
S Rathan, CJ Ankeny, S Arjunon, Z Ferdous, S Kumar, ...
Scientific reports 6 (1), 25397, 2016
512016
Mechanosensitive microRNA-181b regulates aortic valve endothelial matrix degradation by targeting TIMP3
JM Heath, J Fernandez Esmerats, L Khambouneheuang, S Kumar, ...
Cardiovascular engineering and technology 9, 141-150, 2018
492018
Suture forces in undersized mitral annuloplasty: novel device and measurements
AW Siefert, EL Pierce, M Lee, MØ Jensen, C Aoki, S Takebayashi, ...
The Annals of thoracic surgery 98 (1), 305-309, 2014
242014
Hypoxia inducible factor 1α inhibitor PX-478 reduces atherosclerosis in mice
N Villa-Roel, K Ryu, L Gu, JF Esmerats, DW Kang, S Kumar, H Jo
Atherosclerosis 344, 20-30, 2022
172022
miR-214 is stretch-sensitive in aortic valve and inhibits aortic valve calcification
MT Salim, JF Esmerats, S Arjunon, N Villa-Roel, RM Nerem, H Jo, ...
Annals of biomedical engineering 47, 1106-1115, 2019
152019
Hemodynamics and mechanobiology of aortic valve calcification
JF Esmerats, J Heath, A Rezvan, H Jo
Biomedical Engineering: Frontier Research and Converging Technologies, 237-261, 2016
22016
Methods and compositions for managing vascular conditions using miR-483 mimics and HIF1alpha pathway inhibitors
H Jo, JF ESMERATS, N Villa-Roel
US Patent 11,225,660, 2022
12022
Hypoxia Inducible Factor-1α Inhibitor, PX-478, Reduces Atherosclerosis in vivo
N Villa-Roel, L Gu, J Fernandez Esmerats, DW Kang, S Kumar, H Jo
Arteriosclerosis, Thrombosis, and Vascular Biology 40 (Suppl_1), A366-A366, 2020
12020
Shear-Sensitive miRNA-181b Impairs Anti-Inflammatory Signaling in the Aortic Valve Endothelium
J Heath, JF Esmerats, R Simmons, S Kumar, H Jo
Cardiology 134 (2), 167-167, 2016
12016
Role of miRNA-483-3p in Valvular Endothelial Dysfunction
JF Esmerats, J Heath, S Kumar, H Jo
Cardiology 134 (2), 178-178, 2016
12016
Methods and Compositions for Managing Vascular Conditions Using miR-483 Mimics and HIF1alpha Pathway Inhibitors
H Jo, JF ESMERATS, N Villa-Roel
US Patent App. 17/544,801, 2022
2022
Disturbed flow increases UBE2C via loss of miR-483-3p, inducing aortic valve calcification by the HIF1α pathway in endothelial cells
JF Esmerats, N Villa-Roel, S Kumar, L Gu, MT Salim, M Ohh, WR Taylor, ...
Arteriosclerosis, thrombosis, and vascular biology 39 (3), 467, 2019
2019
Shear-Dependent Aortic Valve Endothelial Inflammation and Calcification Are Regulated by O-GlcNAc Modification of MEF2C Transcription Factor
J Heath, H Kim, J Fernandez Esmerats, R Simmons, S Kumar, J Cho, H Jo
Circulation 134 (suppl_1), A19733-A19733, 2016
2016
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