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Lakshmi Santhanam
Lakshmi Santhanam
Verified email at jhmi.edu
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Cited by
Year
Arterial stiffening precedes systolic hypertension in diet-induced obesity
RM Weisbrod, T Shiang, L Al Sayah, JL Fry, S Bajpai, CA Reinhart-King, ...
Hypertension 62 (6), 1105-1110, 2013
3682013
Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats
JH Kim, LJ Bugaj, YJ Oh, TJ Bivalacqua, S Ryoo, KG Soucy, L Santhanam, ...
Journal of applied physiology 107 (4), 1249-1257, 2009
2882009
Endothelial arginase II: a novel target for the treatment of atherosclerosis
S Ryoo, G Gupta, A Benjo, HK Lim, A Camara, G Sikka, HK Lim, J Sohi, ...
Circulation research 102 (8), 923-932, 2008
2732008
Inhibition of NADPH oxidase activation in endothelial cells by ortho-methoxy-substituted catechols
DK Johnson, KJ Schillinger, DM Kwait, CV Hughes, EJ McNamara, ...
Endothelium 9 (3), 191-203, 2002
2262002
Inducible NO Synthase–Dependent S-Nitrosylation and Activation of Arginase1 Contribute to Age-Related Endothelial Dysfunction
L Santhanam, HK Lim, HK Lim, V Miriel, T Brown, M Patel, S Balanson, ...
Circulation research 101 (7), 692-702, 2007
2222007
Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates
JA Mattison, M Wang, M Bernier, J Zhang, SS Park, S Maudsley, SS An, ...
Cell metabolism 20 (1), 183-190, 2014
2202014
Arginase and vascular aging
L Santhanam, DW Christianson, D Nyhan, DE Berkowitz
Journal of applied physiology 105 (5), 1632-1642, 2008
2032008
Decreased S-Nitrosylation of Tissue Transglutaminase Contributes to Age-Related Increases in Vascular Stiffness
L Santhanam, EC Tuday, AK Webb, P Dowzicky, JH Kim, YJ Oh, G Sikka, ...
Circulation research 107 (1), 117-125, 2010
1592010
Upregulation of inducible nitric oxide synthase contributes to attenuated cutaneous vasodilation in essential hypertensive humans
CJ Smith, L Santhanam, RS Bruning, A Stanhewicz, DE Berkowitz, ...
Hypertension 58 (5), 935-942, 2011
1492011
Endothelial nitric oxide synthase mediates cutaneous vasodilation during local heating and is attenuated in middle-aged human skin
RS Bruning, L Santhanam, AE Stanhewicz, CJ Smith, DE Berkowitz, ...
Journal of applied physiology 112 (12), 2019-2026, 2012
1372012
Melanopsin mediates light-dependent relaxation in blood vessels
G Sikka, GP Hussmann, D Pandey, S Cao, D Hori, JT Park, J Steppan, ...
Proceedings of the National Academy of Sciences 111 (50), 17977-17982, 2014
1252014
Sos-mediated activation of rac1 by p66shc
FA Khanday, L Santhanam, K Kasuno, T Yamamori, A Naqvi, J DeRicco, ...
The Journal of cell biology 172 (6), 817-822, 2006
1112006
Rac1 leads to phosphorylation-dependent increase in stability of the p66shc adaptor protein: role in Rac1-induced oxidative stress
FA Khanday, T Yamamori, I Mattagajasingh, Z Zhang, A Bugayenko, ...
Molecular biology of the cell 17 (1), 122-129, 2006
1072006
Arginase modulates myocardial contractility by a nitric oxide synthase 1-dependent mechanism
J Steppan, S Ryoo, KH Schuleri, C Gregg, RK Hasan, AR White, LJ Bugaj, ...
Proceedings of the National Academy of Sciences 103 (12), 4759-4764, 2006
1032006
Oral atorvastatin therapy restores cutaneous microvascular function by decreasing arginase activity in hypercholesterolaemic humans
LA Holowatz, L Santhanam, A Webb, DE Berkowitz, WL Kenney
The Journal of physiology 589 (8), 2093-2103, 2011
1012011
Defining an olfactory receptor function in airway smooth muscle cells
WH Aisenberg, J Huang, W Zhu, P Rajkumar, R Cruz, L Santhanam, ...
Scientific reports 6 (1), 38231, 2016
1002016
Increased angiotensin II sensitivity contributes to microvascular dysfunction in women who have had preeclampsia
AE Stanhewicz, S Jandu, L Santhanam, LM Alexander
Hypertension 70 (2), 382-389, 2017
982017
Oxidative stress contributes to microvascular endothelial dysfunction in men and women with major depressive disorder
JL Greaney, EFH Saunders, L Santhanam, LM Alexander
Circulation research 124 (4), 564-574, 2019
942019
Impaired hydrogen sulfide–mediated vasodilation contributes to microvascular endothelial dysfunction in hypertensive adults
JL Greaney, JL Kutz, SW Shank, S Jandu, L Santhanam, LM Alexander
Hypertension 69 (5), 902-909, 2017
922017
Exercise, vascular stiffness, and tissue transglutaminase
J Steppan, G Sikka, S Jandu, V Barodka, MK Halushka, NA Flavahan, ...
Journal of the American Heart Association 3 (2), e000599, 2014
842014
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