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Heather Wang
Heather Wang
chemist
Dirección de correo verificada de merck.com
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Mapping the dark space of chemical reactions with extended nanomole synthesis and MALDI-TOF MS
S Lin, S Dikler, WD Blincoe, RD Ferguson, RP Sheridan, Z Peng, ...
Science 361 (6402), eaar6236, 2018
1602018
pKa measurements for the SAMPL6 prediction challenge for a set of kinase inhibitor-like fragments
M Işık, D Levorse, AS Rustenburg, IE Ndukwe, H Wang, X Wang, ...
Journal of computer-aided molecular design 32, 1117-1138, 2018
482018
Introducing online multicolumn two-dimensional liquid chromatography screening for facile selection of stationary and mobile phase conditions in both dimensions
H Wang, HR Herderschee, R Bennett, M Potapenko, CJ Pickens, ...
Journal of Chromatography A 1622, 460895, 2020
432020
Mapping the separation landscape in two-dimensional liquid chromatography: blueprints for efficient analysis and purification of pharmaceuticals enabled by computer-assisted …
DM Makey, V Shchurik, H Wang, HR Lhotka, DR Stoll, A Vazhentsev, ...
Analytical Chemistry 93 (2), 964-972, 2020
302020
Enantioselective UHPLC Screening Combined with In Silico Modeling for Streamlined Development of Ultrafast Enantiopurity Assays
GL Losacco, H Wang, IA Haidar Ahmad, J DaSilva, AA Makarov, ...
Analytical Chemistry 94 (3), 1804-1812, 2021
292021
Kilo-Scale Electrochemical Oxidation of a Thioether to a Sulfone: A Workflow for Scaling up Electrosynthesis
C Bottecchia, D Lehnherr, F Lévesque, M Reibarkh, Y Ji, VL Rodrigues, ...
Organic Process Research & Development 26 (8), 2423-2437, 2022
282022
Use of MALDI-MS combined with differential hydrogen–deuterium exchange for semiautomated protein global conformational screening
GF Pirrone, H Wang, N Canfield, AS Chin, TA Rhodes, AA Makarov
Analytical Chemistry 89 (16), 8351-8357, 2017
242017
In Silico Multifactorial Modeling for Streamlined Development and Optimization of Two-Dimensional Liquid Chromatography
IA Haidar Ahmad, DM Makey, H Wang, V Shchurik, AN Singh, DR Stoll, ...
Analytical Chemistry 93 (33), 11532-11539, 2021
182021
Investigation of a flow step clogging incident: a precautionary note on the use of THF in commercial-scale continuous process
NR Rivera, B Kassim, P Grigorov, H Wang, M Armenante, X Bu, A Lekhal, ...
Organic Process Research & Development 23 (11), 2556-2561, 2019
172019
In Silico Method Development of Achiral and Chiral Tandem Column Reversed-phase Liquid Chromatography for Multicomponent Pharmaceutical Mixtures
IA Haidar Ahmad, A Kiffer, RC Barrientos, GL Losacco, A Singh, ...
Analytical Chemistry 94 (9), 4065-4071, 2022
162022
Trapping‐enrichment multi‐dimensional liquid chromatography with on‐line deuterated solvent exchange for streamlined structure elucidation at the microgram scale
IAH Ahmad, GL Losacco, V Shchurik, X Wang, RD Cohen, AN Herron, ...
Angewandte Chemie 134 (21), e202117655, 2022
152022
Enantioselective enzymatic reduction of acrylic acids
C An, MH Shaw, A Tharp, D Verma, H Li, H Wang, X Wang
Organic Letters 22 (21), 8320-8325, 2020
152020
Visualizing and studying frictional heating effects in reversed-phase liquid chromatography using infrared thermal imaging
AA Makarov, BF Mann, EL Regalado, GF Pirrone, C Sun, S Sun, T Nowak, ...
Analytica chimica acta 1018, 1-6, 2018
142018
Automated ion exchange chromatography screening combined with in silico multifactorial simulation for efficient method development and purification of biopharmaceutical targets
GL Losacco, MB Hicks, JO DaSilva, H Wang, M Potapenko, FR Tsay, ...
Analytical and Bioanalytical Chemistry 414 (12), 3581-3591, 2022
102022
Endo Selectivity in the (4 + 3) Cycloaddition of Oxidopyridinium Ions
W Sungnoi, AB Keto, RB Roseli, J Liu, H Wang, C Fu, EL Regalado, ...
Organic Letters 23 (21), 8302-8306, 2021
102021
Multiple‐injection high‐throughput gas chromatography analysis
W Schafer, H Wang, CJ Welch
Journal of Separation Science 39 (15), 2978-2985, 2016
92016
Charged aerosol detection in early and late-stage pharmaceutical development: selection of regression models at optimum power function value
IAH Ahmad, A Blasko, H Wang, T Lu, I Mangion, EL Regalado
Journal of Chromatography A 1641, 461997, 2021
82021
Effects of pressure and frictional heating on protein separation using monolithic columns in reversed-phase chromatography
BF Mann, AA Makarov, H Wang, CJ Welch
Journal of Chromatography A 1489, 58-64, 2017
82017
Automated Hydrophobic Interaction Chromatography Screening Combined with In Silico Optimization as a Framework for Nondenaturing Analysis and Purification …
RC Barrientos, GL Losacco, M Azizi, H Wang, AN Nguyen, V Shchurik, ...
Analytical Chemistry 94 (49), 17131-17141, 2022
72022
Selective Plate-Based Assay for Trace EDTA Analysis via Boron Trifluoride-methanol Derivatization UHPLC-QqQ-MS/MS Enabling Biologic and Vaccine Processes
R Bennett, RD Cohen, H Wang, T Pereira, MA Haverick, JW Loughney, ...
Analytical Chemistry 94 (3), 1678-1685, 2021
72021
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