Nicolas Grillet
Nicolas Grillet
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TMHS is an integral component of the mechanotransduction machinery of cochlear hair cells
W Xiong, N Grillet, HM Elledge, TFJ Wagner, B Zhao, KR Johnson, ...
Cell 151 (6), 1283-1295, 2012
A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function
M Schwander, A Sczaniecka, N Grillet, JS Bailey, M Avenarius, ...
Journal of Neuroscience 27 (9), 2163-2175, 2007
Harmonin mutations cause mechanotransduction defects in cochlear hair cells
N Grillet, W Xiong, A Reynolds, P Kazmierczak, T Sato, C Lillo, ...
Neuron 62 (3), 375-387, 2009
Generation and characterization of Rgs4 mutant mice
N Grillet, A Pattyn, C Contet, BL Kieffer, C Goridis, JF Brunet
Molecular and cellular biology 25 (10), 4221-4228, 2005
Sphingosine 1-phosphate (S1P) signaling is required for maintenance of hair cells mainly via activation of S1P2
DR Herr, N Grillet, M Schwander, R Rivera, U Müller, J Chun
Journal of Neuroscience 27 (6), 1474-1478, 2007
TMIE is an essential component of the mechanotransduction machinery of cochlear hair cells
B Zhao, Z Wu, N Grillet, L Yan, W Xiong, S Harkins-Perry, U Müller
Neuron 84 (5), 954-967, 2014
Mutations in LOXHD1, an evolutionarily conserved stereociliary protein, disrupt hair cell function in mice and cause progressive hearing loss in humans
N Grillet, M Schwander, MS Hildebrand, A Sczaniecka, A Kolatkar, ...
The American Journal of Human Genetics 85 (3), 328-337, 2009
Loss-of-function mutations of ILDR1 cause autosomal-recessive hearing impairment DFNB42
G Borck, AU Rehman, K Lee, HM Pogoda, N Kakar, S Von Ameln, ...
The American Journal of Human Genetics 88 (2), 127-137, 2011
Regulation of PCDH15 function in mechanosensory hair cells by alternative splicing of the cytoplasmic domain
SW Webb, N Grillet, LR Andrade, W Xiong, L Swarthout, CC Della Santina, ...
Development 138 (8), 1607-1617, 2011
Two-dimensional cochlear micromechanics measured in vivo demonstrate radial tuning within the mouse organ of Corti
HY Lee, PD Raphael, A Xia, J Kim, N Grillet, BE Applegate, AKE Bowden, ...
Journal of Neuroscience 36 (31), 8160-8173, 2016
Dynamic expression of RGS4 in the developing nervous system and regulation by the neural type-specific transcription factor Phox2b
N Grillet, V Dubreuil, HD Dufour, JF Brunet
Journal of Neuroscience 23 (33), 10613-10621, 2003
Mechanosensory hair cells express two molecularly distinct mechanotransduction channels
Z Wu, N Grillet, B Zhao, C Cunningham, S Harkins-Perry, B Coste, ...
Nature neuroscience 20 (1), 24-33, 2017
Regulator of G protein signaling-4 controls fatty acid and glucose homeostasis
I Iankova, C Chavey, C Clapé, C Colomer, NC Guérineau, N Grillet, ...
Endocrinology 149 (11), 5706-5712, 2008
Using injectoporation to deliver genes to mechanosensory hair cells
W Xiong, T Wagner, L Yan, N Grillet, U Müller
Nature protocols 9 (10), 2438-2449, 2014
Responsiveness to neurturin of subpopulations of embryonic rat spinal motoneuron does not correlate with expression of GFRα1 or GFRα2
A Garcès, J Livet, N Grillet, CE Henderson, O Delapeyrière
Developmental dynamics: an official publication of the American Association …, 2001
The mechanotransduction machinery of hair cells
N Grillet, P Kazmierczak, W Xiong, M Schwander, A Reynolds, ...
Science signaling 2 (85), pt5-pt5, 2009
Thrombospondins 1 and 2 are important for afferent synapse formation and function in the inner ear
D Mendus, S Sundaresan, N Grillet, F Wangsawihardja, R Leu, U Müller, ...
European Journal of Neuroscience 39 (8), 1256-1267, 2014
Neuroplastin isoform Np55 is expressed in the stereocilia of outer hair cells and required for normal outer hair cell function
WZ Zeng, N Grillet, JB Dewey, A Trouillet, JF Krey, PG Barr-Gillespie, ...
Journal of Neuroscience 36 (35), 9201-9216, 2016
Osmotic stabilization prevents cochlear synaptopathy after blast trauma
J Kim, A Xia, N Grillet, BE Applegate, JS Oghalai
Proceedings of the National Academy of Sciences 115 (21), E4853-E4860, 2018
Genetics of progressive hearing loss: a link between hearing impairment and dysfunction of mechanosensory hair cells
N Grillet, U Müller
Future neurology 5 (1), 9-12, 2010
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Artículos 1–20