Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy JT Hinson, A Chopra, N Nafissi, WJ Polacheck, CC Benson, S Swist, ... Science 349 (6251), 982-986, 2015 | 666 | 2015 |
Single-cell resolution of temporal gene expression during heart development DM DeLaughter, AG Bick, H Wakimoto, D McKean, JM Gorham, ... Developmental cell 39 (4), 480-490, 2016 | 436 | 2016 |
Missense Mutations in the BCS1L Gene as a Cause of the Björnstad Syndrome JT Hinson, VR Fantin, J Schönberger, N Breivik, G Siem, B McDonough, ... New England Journal of Medicine 356 (8), 809-819, 2007 | 239 | 2007 |
SARS-CoV-2 infects human engineered heart tissues and models COVID-19 myocarditis AL Bailey, O Dmytrenko, L Greenberg, AL Bredemeyer, P Ma, J Liu, ... Basic to Translational Science 6 (4), 331-345, 2021 | 180 | 2021 |
Force generation via β-cardiac myosin, titin, and α-actinin drives cardiac sarcomere assembly from cell-matrix adhesions A Chopra, ML Kutys, K Zhang, WJ Polacheck, CC Sheng, RJ Luu, ... Developmental cell 44 (1), 87-96. e5, 2018 | 154 | 2018 |
Gene delivery to pig coronary arteries from stents carrying antibody-tethered adenovirus BD Klugherz, C Song, S DeFelice, X Cui, Z Lu, J Connolly, JT Hinson, ... Human gene therapy 13 (3), 443-454, 2002 | 136 | 2002 |
Poison exon splicing regulates a coordinated network of SR protein expression during differentiation and tumorigenesis NK Leclair, M Brugiolo, L Urbanski, SC Lawson, K Thakar, M Yurieva, ... Molecular Cell 80 (4), 648-665. e9, 2020 | 121 | 2020 |
A contraction stress model of hypertrophic cardiomyopathy due to sarcomere mutations R Cohn, K Thakar, A Lowe, FA Ladha, AM Pettinato, R Romano, ... Stem cell reports 12 (1), 71-83, 2019 | 113 | 2019 |
The NIH somatic cell genome editing program K Saha, EJ Sontheimer, PJ Brooks, MR Dwinell, CA Gersbach, DR Liu, ... Nature 592 (7853), 195-204, 2021 | 111 | 2021 |
Integrative analysis of PRKAG2 cardiomyopathy iPS and microtissue models identifies AMPK as a regulator of metabolism, survival, and fibrosis JT Hinson, A Chopra, A Lowe, CC Sheng, RM Gupta, R Kuppusamy, ... Cell reports 17 (12), 3292-3304, 2016 | 102 | 2016 |
Localized adenovirus gene delivery using antiviral IgG complexation RJ Levy, C Song, S Tallapragada, S DeFelice, JT Hinson, N Vyavahare, ... Gene therapy 8 (9), 659-667, 2001 | 79 | 2001 |
Telomere shortening is a hallmark of genetic cardiomyopathies ACY Chang, ACH Chang, A Kirillova, K Sasagawa, W Su, G Weber, J Lin, ... Proceedings of the National Academy of Sciences 115 (37), 9276-9281, 2018 | 70 | 2018 |
Myofilament mechanical performance is enhanced by R403Q myosin in mouse myocardium independent of sex BM Palmer, Y Wang, P Teekakirikul, JT Hinson, D Fatkin, S Strouse, ... American Journal of Physiology-Heart and Circulatory Physiology 294 (4 …, 2008 | 62 | 2008 |
Bisphosphonate derivatized polyurethanes resist calcification I Alferiev, N Vyavahare, C Song, J Connolly, JT Hinson, Z Lu, ... Biomaterials 22 (19), 2683-2693, 2001 | 46 | 2001 |
Development of a Cardiac Sarcomere Functional Genomics Platform to Enable Scalable Interrogation of Human TNNT2 Variants AM Pettinato, FA Ladha, DJ Mellert, N Legere, R Cohn, R Romano, ... Circulation 142 (23), 2262-2275, 2020 | 40 | 2020 |
Adult mouse fibroblasts retain organ-specific transcriptomic identity E Forte, M Ramialison, HT Nim, M Mara, JY Li, R Cohn, SL Daigle, S Boyd, ... Elife 11, e71008, 2022 | 28 | 2022 |
Reading Frame Repair of TTN Truncation Variants Restores Titin Quantity and Functions R Romano, S Ghahremani, T Zimmerman, N Legere, K Thakar, FA Ladha, ... Circulation 145 (3), 194-205, 2022 | 24 | 2022 |
Sarcomere function activates a p53-dependent DNA damage response that promotes polyploidization and limits in vivo cell engraftment AM Pettinato, D Yoo, J VanOudenhove, YS Chen, R Cohn, FA Ladha, ... Cell reports 35 (5), 2021 | 20 | 2021 |
High reactivity of alkyl sulfides towards epoxides under conditions of collagen fixation—a convenient approach to 2-amino-4-butyrolactones IS Alferiev, JT Hinson, M Ogle, E Breuer, RJ Levy Biomaterials 22 (18), 2501-2506, 2001 | 20 | 2001 |
Detecting cardiovascular protein-protein interactions by proximity proteomics JS Kushner, G Liu, RJ Eisert, GA Bradshaw, GS Pitt, JT Hinson, ... Circulation research 130 (2), 273-287, 2022 | 17 | 2022 |