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J. Travis Hinson
J. Travis Hinson
UConn Health
Dirección de correo verificada de uchc.edu
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Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy
JT Hinson, A Chopra, N Nafissi, WJ Polacheck, CC Benson, S Swist, ...
Science 349 (6251), 982-986, 2015
6662015
Single-cell resolution of temporal gene expression during heart development
DM DeLaughter, AG Bick, H Wakimoto, D McKean, JM Gorham, ...
Developmental cell 39 (4), 480-490, 2016
4362016
Missense Mutations in the BCS1L Gene as a Cause of the Björnstad Syndrome
JT Hinson, VR Fantin, J Schönberger, N Breivik, G Siem, B McDonough, ...
New England Journal of Medicine 356 (8), 809-819, 2007
2392007
SARS-CoV-2 infects human engineered heart tissues and models COVID-19 myocarditis
AL Bailey, O Dmytrenko, L Greenberg, AL Bredemeyer, P Ma, J Liu, ...
Basic to Translational Science 6 (4), 331-345, 2021
1802021
Force generation via β-cardiac myosin, titin, and α-actinin drives cardiac sarcomere assembly from cell-matrix adhesions
A Chopra, ML Kutys, K Zhang, WJ Polacheck, CC Sheng, RJ Luu, ...
Developmental cell 44 (1), 87-96. e5, 2018
1542018
Gene delivery to pig coronary arteries from stents carrying antibody-tethered adenovirus
BD Klugherz, C Song, S DeFelice, X Cui, Z Lu, J Connolly, JT Hinson, ...
Human gene therapy 13 (3), 443-454, 2002
1362002
Poison exon splicing regulates a coordinated network of SR protein expression during differentiation and tumorigenesis
NK Leclair, M Brugiolo, L Urbanski, SC Lawson, K Thakar, M Yurieva, ...
Molecular Cell 80 (4), 648-665. e9, 2020
1212020
A contraction stress model of hypertrophic cardiomyopathy due to sarcomere mutations
R Cohn, K Thakar, A Lowe, FA Ladha, AM Pettinato, R Romano, ...
Stem cell reports 12 (1), 71-83, 2019
1132019
The NIH somatic cell genome editing program
K Saha, EJ Sontheimer, PJ Brooks, MR Dwinell, CA Gersbach, DR Liu, ...
Nature 592 (7853), 195-204, 2021
1112021
Integrative analysis of PRKAG2 cardiomyopathy iPS and microtissue models identifies AMPK as a regulator of metabolism, survival, and fibrosis
JT Hinson, A Chopra, A Lowe, CC Sheng, RM Gupta, R Kuppusamy, ...
Cell reports 17 (12), 3292-3304, 2016
1022016
Localized adenovirus gene delivery using antiviral IgG complexation
RJ Levy, C Song, S Tallapragada, S DeFelice, JT Hinson, N Vyavahare, ...
Gene therapy 8 (9), 659-667, 2001
792001
Telomere shortening is a hallmark of genetic cardiomyopathies
ACY Chang, ACH Chang, A Kirillova, K Sasagawa, W Su, G Weber, J Lin, ...
Proceedings of the National Academy of Sciences 115 (37), 9276-9281, 2018
702018
Myofilament mechanical performance is enhanced by R403Q myosin in mouse myocardium independent of sex
BM Palmer, Y Wang, P Teekakirikul, JT Hinson, D Fatkin, S Strouse, ...
American Journal of Physiology-Heart and Circulatory Physiology 294 (4 …, 2008
622008
Bisphosphonate derivatized polyurethanes resist calcification
I Alferiev, N Vyavahare, C Song, J Connolly, JT Hinson, Z Lu, ...
Biomaterials 22 (19), 2683-2693, 2001
462001
Development of a Cardiac Sarcomere Functional Genomics Platform to Enable Scalable Interrogation of Human TNNT2 Variants
AM Pettinato, FA Ladha, DJ Mellert, N Legere, R Cohn, R Romano, ...
Circulation 142 (23), 2262-2275, 2020
402020
Adult mouse fibroblasts retain organ-specific transcriptomic identity
E Forte, M Ramialison, HT Nim, M Mara, JY Li, R Cohn, SL Daigle, S Boyd, ...
Elife 11, e71008, 2022
282022
Reading Frame Repair of TTN Truncation Variants Restores Titin Quantity and Functions
R Romano, S Ghahremani, T Zimmerman, N Legere, K Thakar, FA Ladha, ...
Circulation 145 (3), 194-205, 2022
242022
Sarcomere function activates a p53-dependent DNA damage response that promotes polyploidization and limits in vivo cell engraftment
AM Pettinato, D Yoo, J VanOudenhove, YS Chen, R Cohn, FA Ladha, ...
Cell reports 35 (5), 2021
202021
High reactivity of alkyl sulfides towards epoxides under conditions of collagen fixation—a convenient approach to 2-amino-4-butyrolactones
IS Alferiev, JT Hinson, M Ogle, E Breuer, RJ Levy
Biomaterials 22 (18), 2501-2506, 2001
202001
Detecting cardiovascular protein-protein interactions by proximity proteomics
JS Kushner, G Liu, RJ Eisert, GA Bradshaw, GS Pitt, JT Hinson, ...
Circulation research 130 (2), 273-287, 2022
172022
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