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Klaus Mauch
Klaus Mauch
Insilico Biotechnology AG
Dirección de correo verificada de insilico-biotechnology.com - Página principal
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Dynamic modeling of the central carbon metabolism of Escherichia coli
C Chassagnole, N Noisommit‐Rizzi, JW Schmid, K Mauch, M Reuss
Biotechnology and bioengineering 79 (1), 53-73, 2002
6802002
Optimal re-design of primary metabolism in Escherichia coli using linlog kinetics
D Visser, JW Schmid, K Mauch, M Reuss, JJ Heijnen
Metabolic Engineering 6 (4), 378-390, 2004
1332004
Metabolic flux analysis in Escherichia coli by integrating isotopic dynamic and isotopic stationary 13C labeling data
J Schaub, K Mauch, M Reuss
Biotechnology and bioengineering 99 (5), 1170-1185, 2008
1212008
Identification of metabolic fluxes in hepatic cells from transient 13C‐labeling experiments: Part I. Experimental observations
U Hofmann, K Maier, A Niebel, G Vacun, M Reuss, K Mauch
Biotechnology and bioengineering 100 (2), 344-354, 2008
1082008
Bridging the layers: towards integration of signal transduction, regulation and metabolism into mathematical models
E Gonçalves, J Bucher, A Ryll, J Niklas, K Mauch, S Klamt, M Rocha, ...
Molecular BioSystems 9 (7), 1576-1583, 2013
1052013
Identification of metabolic fluxes in hepatic cells from transient 13C‐labeling experiments: Part II. Flux estimation
K Maier, U Hofmann, M Reuss, K Mauch
Biotechnology and bioengineering 100 (2), 355-370, 2008
1042008
Integration of physiology and fluid dynamics
S Schmalzriedt, M Jenne, K Mauch, M Reuss
Process integration in biochemical engineering, 19-68, 2003
892003
Metabolic design based on a coupled gene expression—metabolic network model of tryptophan production in Escherichia coli
JW Schmid, K Mauch, M Reuss, ED Gilles, A Kremling
Metabolic Engineering 6 (4), 364-377, 2004
832004
BioPreDyn-bench: a suite of benchmark problems for dynamic modelling in systems biology
AF Villaverde, D Henriques, K Smallbone, S Bongard, J Schmid, ...
BMC systems biology 9 (1), 1-15, 2015
792015
Determination of in vivo kinetics of the starvation-induced Hxt5 glucose transporter of Saccharomyces cerevisiae
S Buziol, J Becker, A Baumeister, S Jung, K Mauch, M Reuss, E Boles
FEMS Yeast Research 2 (3), 283-291, 2002
672002
Tendency modeling: a new approach to obtain simplified kinetic models of metabolism applied to Saccharomyces cerevisiae
D Visser, R van der Heijden, K Mauch, M Reuss, S Heijnen
Metabolic Engineering 2 (3), 252-275, 2000
672000
Quantification of statin effects on hepatic cholesterol synthesis by transient 13C-flux analysis
K Maier, U Hofmann, A Bauer, A Niebel, G Vacun, M Reuss, K Mauch
Metabolic Engineering 11 (4-5), 292-309, 2009
612009
A multi-scale modeling framework for individualized, spatiotemporal prediction of drug effects and toxicological risk
JG Diaz Ochoa, J Bucher, ARR Péry, JM Zaldivar Comenges, J Niklas, ...
Frontiers in pharmacology 3, 204, 2013
582013
Dynamic sensitivity analysis for metabolic systems
K Mauch, S Arnold, M Reuss
Chemical Engineering Science 52 (15), 2589-2598, 1997
571997
Dynamics and control of the central carbon metabolism in hepatoma cells
K Maier, U Hofmann, M Reuss, K Mauch
BMC systems biology 4 (1), 1-28, 2010
472010
Metabolic engineering with multi-objective optimization of kinetic models
AF Villaverde, S Bongard, K Mauch, E Balsa-Canto, JR Banga
Journal of biotechnology 222, 1-8, 2016
332016
Computer-aided design of metabolic networks
K Mauch, S Buziol, J Schmid, M Reuss
AIChE Symposium Series, 82-91, 2002
302002
A guide to gene regulatory network inference for obtaining predictive solutions: Underlying assumptions and fundamental biological and data constraints
S Barbosa, B Niebel, S Wolf, K Mauch, R Takors
Biosystems 174, 37-48, 2018
242018
Multiscale modelling approaches for assessing cosmetic ingredients safety
FY Bois, JGD Ochoa, M Gajewska, S Kovarich, K Mauch, A Paini, A Péry, ...
Toxicology 392, 130-139, 2017
242017
A consensus approach for estimating the predictive accuracy of dynamic models in biology
AF Villaverde, S Bongard, K Mauch, D Müller, E Balsa-Canto, J Schmid, ...
Computer methods and programs in biomedicine 119 (1), 17-28, 2015
232015
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Artículos 1–20