Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity RH McMahan, L Golden-Mason, MI Nishimura, BJ McMahon, M Kemper, ... The Journal of clinical investigation 120 (12), 4546-4557, 2010 | 373 | 2010 |
High‐fat and high‐sucrose (western) diet induces steatohepatitis that is dependent on fructokinase T Ishimoto, MA Lanaspa, CJ Rivard, CA Roncal‐Jimenez, DJ Orlicky, ... Hepatology 58 (5), 1632-1643, 2013 | 354 | 2013 |
Bile acid receptor activation modulates hepatic monocyte activity and improves nonalcoholic fatty liver disease RH McMahan, XX Wang, LL Cheng, T Krisko, M Smith, K El Kasmi, ... Journal of Biological Chemistry 288 (17), 11761-11770, 2013 | 234 | 2013 |
A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection JA Mengshol, L Golden-Mason, T Arikawa, M Smith, T Niki, R McWilliams, ... PloS one 5 (3), e9504, 2010 | 219 | 2010 |
Relating TCR-peptide-MHC affinity to immunogenicity for the design of tumor vaccines RH McMahan, JA McWilliams, KR Jordan, SW Dow, DB Wilson, ... The Journal of clinical investigation 116 (9), 2543-2551, 2006 | 157 | 2006 |
Galectin-9 functionally impairs natural killer cells in humans and mice L Golden-Mason, RH McMahan, M Strong, R Reisdorph, S Mahaffey, ... Journal of virology 87 (9), 4835-4845, 2013 | 129 | 2013 |
Dietary lipids differentially shape nonalcoholic steatohepatitis progression and the transcriptome of Kupffer cells and infiltrating macrophages B McGettigan, R McMahan, D Orlicky, M Burchill, T Danhorn, P Francis, ... Hepatology 70 (1), 67-83, 2019 | 88 | 2019 |
Mobilizing the low-avidity T cell repertoire to kill tumors RH McMahan, JE Slansky Seminars in cancer biology 17 (4), 317-329, 2007 | 76 | 2007 |
Peptide vaccines prevent tumor growth by activating T cells that respond to native tumor antigens KR Jordan, RH McMahan, CB Kemmler, JW Kappler, JE Slansky Proceedings of the National Academy of Sciences 107 (10), 4652-4657, 2010 | 70 | 2010 |
Perilipin‐2 promotes obesity and progressive fatty liver disease in mice through mechanistically distinct hepatocyte and extra‐hepatocyte actions DJ Orlicky, AE Libby, ES Bales, RH McMahan, J Monks, FG La Rosa, ... The Journal of physiology 597 (6), 1565-1584, 2019 | 69 | 2019 |
Macrophages mediate lung inflammation in a mouse model of ischemic acute kidney injury C Altmann, A Andres-Hernando, RH McMahan, N Ahuja, Z He, CJ Rivard, ... American Journal of Physiology-Renal Physiology 302 (4), F421-F432, 2012 | 62 | 2012 |
How an alloreactive T-cell receptor achieves peptide and MHC specificity Y Wang, NK Singh, TT Spear, LM Hellman, KH Piepenbrink, ... Proceedings of the National Academy of Sciences 114 (24), E4792-E4801, 2017 | 52 | 2017 |
Free fatty acids differentially downregulate chemokines in liver sinusoidal endothelial cells: insights into non-alcoholic fatty liver disease RH McMahan, CE Porsche, MG Edwards, HR Rosen PLoS One 11 (7), e0159217, 2016 | 47 | 2016 |
Age-dependent tolerance to an endogenous tumor-associated antigen JA McWilliams, RT Sullivan, KR Jordan, RH McMahan, CB Kemmler, ... Vaccine 26 (15), 1863-1873, 2008 | 47 | 2008 |
Age-related changes in intestinal immunity and the microbiome T Walrath, KU Dyamenahalli, HJ Hulsebus, RL McCullough, JP Idrovo, ... Journal of Leucocyte Biology 109 (6), 1045-1061, 2021 | 46 | 2021 |
Genetic diversity of near genome-wide hepatitis C virus sequences during chronic infection: evidence for protein structural conservation over time H Li, AL Hughes, N Bano, S McArdle, S Livingston, H Deubner, ... PloS one 6 (5), e19562, 2011 | 38 | 2011 |
Specificity of regulatory CD4+CD25+ T cells for self‐T cell receptor determinants AC Buenafe, L Tsaknaridis, L Spencer, KS Hicks, RH McMahan, L Watson, ... Journal of neuroscience research 76 (1), 129-140, 2004 | 34 | 2004 |
Sevelamer improves steatohepatitis, inhibits liver and intestinal farnesoid X receptor (FXR), and reverses innate immune dysregulation in a mouse model of non-alcoholic fatty … BM McGettigan, RH McMahan, Y Luo, XX Wang, DJ Orlicky, C Porsche, ... Journal of Biological Chemistry 291 (44), 23058-23067, 2016 | 33 | 2016 |
Baculovirus-infected insect cells expressing peptide-MHC complexes elicit protective antitumor immunity KR Jordan, RH McMahan, JZ Oh, MR Pipeling, DM Pardoll, RM Kedl, ... The Journal of Immunology 180 (1), 188-197, 2008 | 33 | 2008 |
Early and late changes in natural killer cells in response to ledipasvir/sofosbuvir treatment L Golden‐Mason, RH McMahan, MS Kriss, AL Kilgore, L Cheng, RJ Dran, ... Hepatology communications 2 (4), 364-375, 2018 | 32 | 2018 |