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Santosh Kumar, Ph.D.
Santosh Kumar, Ph.D.
Lombardi Cancer Center, Department of Oncology, Georgetown University Medical Center,
Dirección de correo verificada de georgetown.edu
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Osteopontin as a therapeutic target for cancer
M Bandopadhyay, A Bulbule, R Butti, G Chakraborty, P Ghorpade, ...
Expert Opinion on Therapeutic Targets 18 ((8)), 883-95., 2014
1442014
Semaphorin 3A suppresses tumor growth and metastasis in mice melanoma model
G Chakraborty, S Kumar, R Mishra, TV Patil, GC Kundu
PloS one 7 (3), e33633, 2012
962012
Osteopontin: a potentially important therapeutic target in cancer
M Ahmed, R Behera, G Chakraborty, S Jain, V Kumar, P Sharma, ...
Expert opinion on therapeutic targets 15 (9), 1113-1126, 2011
862011
Andrographolide Inhibits Osteopontin Expression and Breast Tumor Growth Through Down Regulation of PI3 Kinase/Akt Signaling Pathway
S Kumar, H S Patil, P Sharma, D Kumar, S Dasari, V G Puranik, ...
Current Molecular Medicine 12 (8), 952-966, 2012
842012
Notch1-MAPK signaling axis regulates CD133+ cancer stem cell-mediated melanoma growth and angiogenesis
D Kumar, S Kumar, M Gorain, D Tomar, HS Patil, NNV Radharani, ...
Journal of Investigative Dermatology 136 (12), 2462-2474, 2016
752016
Curcumin suppresses breast tumor angiogenesis by abrogating osteopontin-induced VEGF expression
G Chakraborty, S Jain, S Kale, R Raja, S Kumar, R Mishra, GC Kundu
Molecular Medicine Reports 1 (5), 641-646, 2008
692008
Space radiation triggers persistent stress response, increases senescent signaling, and decreases cell migration in mouse intestine
S Kumar, S Suman, AJ Fornace Jr, K Datta
Proceedings of the National Academy of Sciences 115 (42), E9832-E9841, 2018
662018
Epoxyazadiradione suppresses breast tumor growth through mitochondrial depolarization and caspase-dependent apoptosis by targeting PI3K/Akt pathway
D Kumar, S Haldar, M Gorain, S Kumar, FA Mulani, AS Yadav, L Miele, ...
BMC cancer 18 (1), 52, 2018
622018
Transcriptional regulation of human osteopontin promoter by histone deacetylase inhibitor, trichostatin A in cervical cancer cells
P Sharma, S Kumar, GC Kundu
Molecular cancer 9 (1), 178, 2010
582010
Functional characterization of stromal osteopontin in melanoma progression and metastasis
S Kumar, P Sharma, D Kumar, G Chakraborty, M Gorain, GC Kundu
PloS one 8 (7), e69116, 2013
552013
Relative biological effectiveness of energetic heavy ions for intestinal tumorigenesis shows male preponderance and radiation type and energy dependence in APC1638N/+ mice
S Suman, S Kumar, BH Moon, SJ Strawn, H Thakor, Z Fan, JW Shay, ...
International Journal of Radiation Oncology* Biology* Physics 95 (1), 131-138, 2016
482016
Intestinal stem cells acquire premature senescence and senescence associated secretory phenotype concurrent with persistent DNA damage after heavy ion radiation in mice
S Kumar, S Suman, AJ Fornace Jr, K Datta
Aging (Albany NY) 11 (12), 4145, 2019
382019
Modified dipeptide-based nanoparticles: vehicles for targeted tumor drug delivery
JJ Panda, A Kaul, S Kumar, S Alam, AK Mishra, GC Kundu, VS Chauhan
Nanomedicine 8 (12), 1927-1942, 2013
362013
Scaling human cancer risks from low LET to high LET when dose-effect relationships are complex
I Shuryak, AJ Fornace Jr, K Datta, S Suman, S Kumar, RK Sachs, ...
Radiation research 187 (4), 486-492, 2017
342017
Colorectal carcinogenesis, radiation quality, and the ubiquitin-proteasome pathway
K Datta, S Suman, S Kumar, AJ Fornace Jr
Journal of cancer 7 (2), 174, 2016
252016
Space radiation exposure persistently increased leptin and IGF1 in serum and activated leptin-IGF1 signaling axis in mouse intestine
S Suman, S Kumar, AJ Fornace, K Datta
Scientific reports 6, 31853, 2016
192016
The potential of class 3 semaphorins as both targets and therapeutics in cancer
R Mishra, D Kumar, D Tomar, G Chakraborty, S Kumar, GC Kundu
Expert Opinion on Therapeutic Targets 19 (3), 427-442, 2015
182015
The effect of carbon irradiation is associated with greater oxidative stress in mouse intestine and colon relative to γ-rays
S Suman, S Kumar, AJ Fornace Jr, K Datta
Free radical research 52 (5), 556-567, 2018
172018
Low and high dose rate heavy ion radiation-induced intestinal and colonic tumorigenesis in APC1638N/+ mice
S Suman, S Kumar, BH Moon, AJ Fornace Jr, K Datta
Life Sciences in Space Research 13, 45-50, 2017
172017
SUMOylation of HP1α supports association with ncRNA to define responsiveness of breast cancer cells to chemotherapy
FM Lin, S Kumar, J Ren, S Karami, S Bahnassy, Y Li, X Zheng, J Wang, ...
Oncotarget 7 (21), 30336, 2016
162016
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