Derin Keskin
Derin Keskin
Broad Institute
Dirección de correo verificada de broadinstitute.org
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Potential regulatory function of human dendritic cells expressing indoleamine 2, 3-dioxygenase
DH Munn, MD Sharma, JR Lee, KG Jhaver, TS Johnson, DB Keskin, ...
Science 297 (5588), 1867-1870, 2002
11622002
An immunogenic personal neoantigen vaccine for patients with melanoma
PA Ott, Z Hu, DB Keskin, SA Shukla, J Sun, DJ Bozym, W Zhang, A Luoma, ...
Nature 547 (7662), 217, 2017
11002017
Cells expressing indoleamine 2, 3-dioxygenase inhibit T cell responses
AL Mellor, DB Keskin, T Johnson, P Chandler, DH Munn
The Journal of Immunology 168 (8), 3771-3776, 2002
3842002
A review of the current use of rituximab in autoimmune diseases
HM Gürcan, DB Keskin, JNH Stern, MA Nitzberg, H Shekhani, AR Ahmed
International immunopharmacology 9 (1), 10-25, 2009
3342009
TGFβ promotes conversion of CD16+ peripheral blood NK cells into CD16− NK cells with similarities to decidual NK cells
DB Keskin, DSJ Allan, B Rybalov, MM Andzelm, JNH Stern, HD Kopcow, ...
Proceedings of the National Academy of Sciences 104 (9), 3378-3383, 2007
3202007
Functional expression of indoleamine 2,3-dioxygenase by murine CD8α+ dendritic cells
F Fallarino, C Vacca, C Orabona, ML Belladonna, R Bianchi, B Marshall, ...
International Immunology 14 (1), 65-68, 2002
3022002
Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia
M Rajasagi, SA Shukla, EF Fritsch, DB Keskin, D DeLuca, E Carmona, ...
Blood 124 (3), 453-462, 2014
2892014
Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial
DB Keskin, AJ Anandappa, J Sun, I Tirosh, ND Mathewson, S Li, ...
Nature 565 (7738), 234, 2019
2802019
Mass spectrometry profiling of HLA-associated peptidomes in mono-allelic cells enables more accurate epitope prediction
JG Abelin, DB Keskin, S Sarkizova, CR Hartigan, W Zhang, J Sidney, ...
Immunity 46 (2), 315-326, 2017
2662017
Induction of anti-tumor cytotoxic T cell responses through PLGA-nanoparticle mediated antigen delivery
Z Zhang, S Tongchusak, Y Mizukami, YJ Kang, T Ioji, M Touma, ...
Biomaterials 32 (14), 3666-3678, 2011
1982011
Developmental bias in cleavage-stage mouse blastomeres
I Tabansky, A Lenarcic, RW Draft, K Loulier, DB Keskin, J Rosains, ...
Current Biology 23 (1), 21-31, 2013
1292013
Force-dependent transition in the T-cell receptor β-subunit allosterically regulates peptide discrimination and pMHC bond lifetime
DK Das, Y Feng, RJ Mallis, X Li, DB Keskin, RE Hussey, SK Brady, ...
Proceedings of the National Academy of Sciences 112 (5), 1517-1522, 2015
1242015
Indoleamine 2, 3-dioxygenase, immunosuppression and pregnancy
AL Mellor, P Chandler, GK Lee, T Johnson, DB Keskin, J Lee, DH Munn
Journal of reproductive immunology 57 (1-2), 143-150, 2002
1232002
Tryptophan catabolism and T cell responses
AL Mellor, D Munn, P Chandler, D Keskin, T Johnson, B Marshall, ...
Developments in Tryptophan and Serotonin Metabolism, 27-35, 2003
992003
A conserved E7-derived cytotoxic T lymphocyte epitope expressed on human papillomavirus 16-transformed HLA-A2+ epithelial cancers
AB Riemer, DB Keskin, G Zhang, M Handley, KS Anderson, V Brusic, ...
Journal of Biological Chemistry 285 (38), 29608-29622, 2010
682010
Promoting tolerance to proteolipid protein-induced experimental autoimmune encephalomyelitis through targeting dendritic cells
JNH Stern, DB Keskin, Z Kato, H Waldner, S Schallenberg, A Anderson, ...
Proceedings of the National Academy of Sciences 107 (40), 17280-17285, 2010
642010
Bioinformatic identification and characterization of human endothelial cell-restricted genes
M Bhasin, L Yuan, DB Keskin, HH Otu, TA Libermann, P Oettgen
BMC genomics 11 (1), 342, 2010
562010
Amino acid copolymer-specific IL-10-secreting regulatory T cells that ameliorate autoimmune diseases in mice
JNH Stern, DB Keskin, H Zhang, HJ Lv, Z Kato, JL Strominger
Proceedings of the National Academy of Sciences 105 (13), 5172-5176, 2008
562008
Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade
SA Shukla, P Bachireddy, B Schilling, C Galonska, Q Zhan, C Bango, ...
Cell 173 (3), 624-633. e8, 2018
552018
Mutated BCR-ABL generates immunogenic T-cell epitopes in CML patients
A Cai, DB Keskin, DS DeLuca, A Alonso, W Zhang, GL Zhang, ...
Clinical Cancer Research 18 (20), 5761-5772, 2012
552012
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Artículos 1–20