| Clinical relevance of DPYD variants c. 1679T> G, c. 1236G> A/HapB3, and c. 1601G> A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta … D Meulendijks, LM Henricks, GS Sonke, MJ Deenen, TK Froehlich, ... The Lancet Oncology 16 (16), 1639-1650, 2015 | 369 | 2015 |
| Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families X Yang, G Leslie, A Doroszuk, S Schneider, J Allen, B Decker, ... Journal of clinical oncology 38 (7), 674-685, 2020 | 351 | 2020 |
| Genetic markers of toxicity from capecitabine and other fluorouracil-based regimens: investigation in the QUASAR2 study, systematic review, and meta-analysis D Rosmarin, C Palles, D Church, E Domingo, A Jones, E Johnstone, ... Journal of Clinical Oncology 32 (10), 1031, 2014 | 262 | 2014 |
| Gain-of-function mutations of PPM1D/Wip1 impair the p53-dependent G1 checkpoint P Kleiblova, IA Shaltiel, J Benada, J evčík, S Pecháčková, P Pohlreich, ... Journal of Cell Biology 201 (4), 511-521, 2013 | 164 | 2013 |
| Women at high risk of breast cancer: Molecular characteristics, clinical presentation and management Z Kleibl, VN Kristensen The Breast 28, 136-144, 2016 | 163 | 2016 |
| CHEK2 Germline Variants in Cancer Predisposition: Stalemate Rather than Checkmate L Stolarova, P Kleiblova, M Janatova, J Soukupova, P Zemankova, ... Cells 9 (12), 2675, 2020 | 126 | 2020 |
| High proportion of recurrent germline mutations in the BRCA1 gene in breast and ovarian cancer patients from the Prague area P Pohlreich, M Zikan, J Stribrna, Z Kleibl, M Janatova, J Kotlas, J Zidovska, ... Breast cancer research 7, 1-9, 2005 | 125 | 2005 |
| Expression of adipokines and estrogen receptors in adipose tissue and placenta of patients with gestational diabetes mellitus P Kleiblova, I Dostalova, M Bartlova, Z Lacinova, I Ticha, V Krejci, ... Molecular and cellular endocrinology 314 (1), 150-156, 2010 | 123 | 2010 |
| The role of ATM in breast cancer development J Prokopcova, Z Kleibl, CM Banwell, P Pohlreich Breast cancer research and treatment 104, 121-128, 2007 | 91 | 2007 |
| Influence of dihydropyrimidine dehydrogenase gene (DPYD) coding sequence variants on the development of fluoropyrimidine-related toxicity in patients with high-grade toxicity … Z Kleibl, J Fidlerova, P Kleiblova, S Kormunda, M Bilek, K Bouskova, ... Neoplasma 56 (4), 303-316, 2009 | 89 | 2009 |
| Identification of deleterious germline CHEK2 mutations and their association with breast and ovarian cancer P Kleiblova, L Stolarova, K Krizova, F Lhota, J Hojny, P Zemankova, ... International journal of cancer 145 (7), 1782-1797, 2019 | 84 | 2019 |
| RNA regulation and cancer development E Scholzová, R Malík, J Ševčík, Z Kleibl Cancer letters 246 (1-2), 12-23, 2007 | 82 | 2007 |
| The CHEK2 c. 1100delC germline mutation rarely contributes to breast cancer development in the Czech Republic Z Kleibl, J Novotny, D Bezdickova, R Malik, P Kleiblova, L Foretova, ... Breast cancer research and treatment 90, 165-167, 2005 | 65 | 2005 |
| Hereditary truncating mutations of DNA repair and other genes in BRCA1/BRCA2/PALB2‐negatively tested breast cancer patients F Lhota, P Zemankova, P Kleiblova, J Soukupova, M Vocka, V Stranecky, ... Clinical genetics 90 (4), 324-333, 2016 | 61 | 2016 |
| The PALB2 Gene Is a Strong Candidate for Clinical Testing in BRCA1- and BRCA2-Negative Hereditary Breast Cancer M Janatova, Z Kleibl, J Stribrna, A Panczak, K Vesela, M Zimovjanova, ... Cancer epidemiology, biomarkers & prevention 22 (12), 2323-2332, 2013 | 56 | 2013 |
| The CHEK2 gene I157T mutation and other alterations in its proximity increase the risk of sporadic colorectal cancer in the Czech population Z Kleibl, O Havranek, I Hlavata, J Novotny, J Sevcik, P Pohlreich, ... European Journal of Cancer 45 (4), 618-624, 2009 | 50 | 2009 |
| Screening for genomic rearrangements in BRCA1 and BRCA2 genes in Czech high-risk breast/ovarian cancer patients: high proportion of population specific alterations in … I Ticha, Z Kleibl, J Stribrna, J Kotlas, M Zimovjanova, M Mateju, M Zikan, ... Breast cancer research and treatment 124, 337-347, 2010 | 46 | 2010 |
| Functional characterization of CHEK2 variants in a Saccharomyces cerevisiae system A Delimitsou, F Fostira, D Kalfakakou, P Apostolou, I Konstantopoulou, ... Human mutation 40 (5), 631-648, 2019 | 45 | 2019 |
| A comprehensive evaluation of pathogenic mutations in primary cutaneous melanomas, including the identification of novel loss-of-function variants I Ticha, J Hojny, R Michalkova, O Kodet, E Krkavcova, N Hajkova, ... Scientific Reports 9 (1), 17050, 2019 | 42 | 2019 |
| Association of Germline CHEK2 Gene Variants with Risk and Prognosis of Non-Hodgkin Lymphoma O Havranek, P Kleiblova, J Hojny, F Lhota, Soucek, Pavel, M Trneny, ... PLoS One 10 (10), e0140819, 2015 | 42 | 2015 |
Michal ZikánDirección de correo verificada de lf1.cuni.cz
