| Synthesis, Biological Evaluation, and Molecular Modeling of Donepezil and N-[(5-(Benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine Hybrids … I Bolea, J Juarez-Jimenez, C de los Rı́os, M Chioua, R Pouplana, ... Journal of medicinal chemistry 54 (24), 8251-8270, 2011 | 239 | 2011 |
| Synthesis and biological evaluation of 3, 6-diamino-1H-pyrazolo [3, 4-b] pyridine derivatives as protein kinase inhibitors M Chioua, A Samadi, E Soriano, O Lozach, L Meijer, J Marco-Contelles Bioorganic & medicinal chemistry letters 19 (16), 4566-4569, 2009 | 107 | 2009 |
| Multitarget‐Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3R Antagonism for Neurodegenerative Diseases ÓM Bautista‐Aguilera, S Hagenow, A Palomino‐Antolin, V Farré‐Alins, ... Angewandte Chemie International Edition 56 (41), 12765-12769, 2017 | 91 | 2017 |
| Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted … A Samadi, C De Los Ríos, I Bolea, M Chioua, I Iriepa, I Moraleda, ... European journal of medicinal chemistry 52, 251-262, 2012 | 91 | 2012 |
| Synthesis, biological assessment and molecular modeling of new multipotent MAO and cholinesterase inhibitors as potential drugs for the treatment of Alzheimer’s disease A Samadi, M Chioua, I Bolea, C De Los Ríos, I Iriepa, I Moraleda, ... European journal of medicinal chemistry 46 (9), 4665-4668, 2011 | 83 | 2011 |
| Synthesis, biological assessment, and molecular modeling of racemic 7-aryl-9, 10, 11, 12-tetrahydro-7H-benzo [7, 8] chromeno [2, 3-b] quinolin-8-amines as potential drugs for … E Maalej, F Chabchoub, MJ Oset-Gasque, M Esquivias-Pérez, ... European journal of medicinal chemistry 54, 750-763, 2012 | 78 | 2012 |
| Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer’s disease: design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR … OM Bautista-Aguilera, G Esteban, M Chioua, K Nikolic, D Agbaba, ... Drug Design, Development and Therapy, 1893-1910, 2014 | 75 | 2014 |
| N-Methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine, a New Cholinesterase and Monoamine Oxidase … OM Bautista-Aguilera, A Samadi, M Chioua, K Nikolic, S Filipic, D Agbaba, ... Journal of medicinal chemistry 57 (24), 10455-10463, 2014 | 70 | 2014 |
| α-Aryl-N-alkyl Nitrones, as Potential Agents for Stroke Treatment: Synthesis, Theoretical Calculations, Antioxidant, Anti-inflammatory, Neuroprotective, and Brain … M Chioua, D Sucunza, E Soriano, D Hadjipavlou-Litina, A Alcázar, ... Journal of medicinal chemistry 55 (1), 153-168, 2012 | 69 | 2012 |
| Synthesis, pharmacological assessment, and molecular modeling of acetylcholinesterase/butyrylcholinesterase inhibitors: effect against amyloid-β-induced neurotoxicity D Silva, M Chioua, A Samadi, P Agostinho, P Garcao, R Lajarín-Cuesta, ... ACS Chemical Neuroscience 4 (4), 547-565, 2013 | 64 | 2013 |
| Pyridonepezils, new dual AChE inhibitors as potential drugs for the treatment of Alzheimer's disease: Synthesis, biological assessment, and molecular modeling A Samadi, M Estrada, C Pérez, MI Rodríguez-Franco, I Iriepa, I Moraleda, ... European journal of medicinal chemistry 57, 296-301, 2012 | 64 | 2012 |
| Synthesis and pharmacological assessment of diversely substituted pyrazolo [3, 4-b] quinoline, and benzo [b] pyrazolo [4, 3-g][1, 8] naphthyridine derivatives D Silva, M Chioua, A Samadi, MC Carreiras, ML Jimeno, E Mendes, ... European journal of medicinal chemistry 46 (9), 4676-4681, 2011 | 64 | 2011 |
| Cholinergic and neuroprotective drugs for the treatment of Alzheimer and neuronal vascular diseases. II. Synthesis, biological assessment, and molecular modelling of new … A Samadi, C Valderas, C De Los Ríos, A Bastida, M Chioua, ... Bioorganic & medicinal chemistry 19 (1), 122-133, 2011 | 64 | 2011 |
| Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer and neuronal vascular diseases. I. Synthesis, biological assessment, and … A Samadi, J Marco-Contelles, E Soriano, M Álvarez-Pérez, M Chioua, ... Bioorganic & medicinal chemistry 18 (16), 5861-5872, 2010 | 63 | 2010 |
| Synthesis, analytical features, and biological relevance of 5-(3′, 4′-Dihydroxyphenyl)-γ-valerolactone, a microbial metabolite derived from the catabolism of dietary flavan-3-ols F Sánchez-Patán, M Chioua, I Garrido, C Cueva, A Samadi, ... Journal of agricultural and food chemistry 59 (13), 7083-7091, 2011 | 62 | 2011 |
| Synthesis and biological assessment of diversely substituted furo [2, 3-b] quinolin-4-amine and pyrrolo [2, 3-b] quinolin-4-amine derivatives, as novel tacrine analogues C Martins, MC Carreiras, R León, C De Los Ríos, M Bartolini, V Andrisano, ... European journal of medicinal chemistry 46 (12), 6119-6130, 2011 | 60 | 2011 |
| Potent anticholinesterasic and neuroprotective pyranotacrines as inhibitors of beta-amyloid aggregation, oxidative stress and tau-phosphorylation for Alzheimer's disease N García-Font, H Hayour, A Belfaitah, J Pedraz, I Moraleda, I Iriepa, ... European journal of medicinal chemistry 118, 178-192, 2016 | 58 | 2016 |
| Tacripyrimidines, the first tacrine-dihydropyrimidine hybrids, as multi-target-directed ligands for Alzheimer's disease M Chioua, E Buzzi, I Moraleda, I Iriepa, M Maj, A Wnorowski, C Giovannini, ... European Journal of Medicinal Chemistry 155, 839-846, 2018 | 57 | 2018 |
| Toxicological and pharmacological evaluation, antioxidant, ADMET and molecular modeling of selected racemic chromenotacrines {11-amino-12-aryl-8, 9, 10, 12-tetrahydro-7H … MJ Oset-Gasque, MP González, J Pérez-Peña, N García-Font, A Romero, ... European Journal of Medicinal Chemistry 74, 491-501, 2014 | 51 | 2014 |
| Synthesis, structure, theoretical and experimental in vitro antioxidant/pharmacological properties of α-aryl, N-alkyl nitrones, as potential agents for the treatment of … A Samadi, E Soriano, J Revuelta, C Valderas, M Chioua, I Garrido, ... Bioorganic & medicinal chemistry 19 (2), 951-960, 2011 | 51 | 2011 |
